ID A0A1I0MWQ7_9FIRM Unreviewed; 426 AA.
AC A0A1I0MWQ7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Cell wall-associated hydrolase, NlpC family {ECO:0000313|EMBL:SEV93337.1};
GN ORFNames=SAMN05216413_0693 {ECO:0000313|EMBL:SEV93337.1};
OS Ruminococcaceae bacterium KH2T8.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX NCBI_TaxID=1855400 {ECO:0000313|EMBL:SEV93337.1, ECO:0000313|Proteomes:UP000198503};
RN [1] {ECO:0000313|EMBL:SEV93337.1, ECO:0000313|Proteomes:UP000198503}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH2T8 {ECO:0000313|EMBL:SEV93337.1,
RC ECO:0000313|Proteomes:UP000198503};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C40 family.
CC {ECO:0000256|ARBA:ARBA00007074}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOIY01000001; SEV93337.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0MWQ7; -.
DR STRING; 1855400.SAMN05216413_0693; -.
DR OrthoDB; 9808890at2; -.
DR Proteomes; UP000198503; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1720.10; endopeptidase domain like (from Nostoc punctiforme); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR000064; NLP_P60_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR003646; SH3-like_bac-type.
DR PANTHER; PTHR47053; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR PANTHER; PTHR47053:SF1; MUREIN DD-ENDOPEPTIDASE MEPH-RELATED; 1.
DR Pfam; PF00877; NLPC_P60; 1.
DR Pfam; PF08239; SH3_3; 1.
DR SMART; SM00287; SH3b; 2.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS51935; NLPC_P60; 1.
DR PROSITE; PS51781; SH3B; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:SEV93337.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198503}.
FT DOMAIN 195..261
FT /note="SH3b"
FT /evidence="ECO:0000259|PROSITE:PS51781"
FT DOMAIN 307..426
FT /note="NlpC/P60"
FT /evidence="ECO:0000259|PROSITE:PS51935"
FT REGION 255..299
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..278
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 281..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 426 AA; 46163 MW; 8ECEBB048A2B0428 CRC64;
MKNNNNRSKI SAGRALLSVL VSASVTVPII CLPIGTREGT SPALQVRRAY AATFPEEELE
EVETPVEDVE VDEYILNGGT ISASYNEGYD PSQTEVQYRD VTTYIVYQAY DQSGLPEELL
DPMYFTQDDT PYYIQTQDTI IKDAPYMDSL TLESIPMGEG VQRIAYGDTW SKIRTRDGVE
GYVLTTSLSY EMVWQDIDRI VWVDTDSLIL RSEASTDSEM IATLHDEDRL RCISIADKWY
KVITEDGLEG YVYISYTTDQ PPPTPTPTPT PVPPPPSNGG GGGGGSSSGG GGTNYNQVVG
GTYENTGNNG QTIANIAESM LGVSYVWGAC SNSAVDCSGL VCYCYGQLGV SLPHQSQSLC
SVGVPVDRED AQPGDIVCWD TGGGSCGHVG IYVGGGQCID ARGRAWGVVY GDIDRHPILT
IRRIYT
//
