ID A0A1I0NBW7_9BACT Unreviewed; 972 AA.
AC A0A1I0NBW7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SAMN05216290_1067 {ECO:0000313|EMBL:SEV98485.1};
OS Roseivirga pacifica.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Roseivirgaceae;
OC Roseivirga.
OX NCBI_TaxID=1267423 {ECO:0000313|EMBL:SEV98485.1, ECO:0000313|Proteomes:UP000199437};
RN [1] {ECO:0000313|Proteomes:UP000199437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.12402 {ECO:0000313|Proteomes:UP000199437};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
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DR EMBL; FOIR01000001; SEV98485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0NBW7; -.
DR STRING; 1267423.SAMN05216290_1067; -.
DR OrthoDB; 9805821at2; -.
DR Proteomes; UP000199437; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR001466; Beta-lactam-related.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00144; Beta-lactamase; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000199437};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..972
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011761208"
FT DOMAIN 47..361
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
FT DOMAIN 587..949
FT /note="Beta-lactamase-related"
FT /evidence="ECO:0000259|Pfam:PF00144"
SQ SEQUENCE 972 AA; 110215 MW; 415AB4D148C02202 CRC64;
MIKKVIWFCF SLLLVNTSLQ AQKIYNKIDT ERQNQWADSI FNAMTPDERL GQLFMVAAYS
NRNEEHYKEI DQLVTEYNVG GLIFFQGGPY RQAKLHNRYQ AEAKVPLMVA MDAEWGIGMR
LDSVYDFPKQ MTLGAIQDDE WVYKMGEEVA NQFKALKMHI NFAPVVDVNV NPNNPVIGYR
SFGEDKYDVA EKGIAYMKGL QDNGIMANAK HFPGHGDTSV DSHHDLPVIN HDTVRMSDTE
LYPFRELMKD SLLSVMVAHL QIPAYDNRKN TPTTLSDKVV TDLLKKDLQF DGLAFTDAMN
MQGVAKYYEP GEADVKALQA GNDVILFPLD VPKAIKQVKK ALKKGELDQA DIDQRVKNVL
RAKYWLGLEG DNMVNMTNLN KRINNDYALM LNKILYQKAI TVVDNQDQLL PVLSLDKKKF
ATVHFGEKAP DEFHRMMDKY AKFEHIQVDT LTDETLDYLS NFDLVVTAYT GITNSPRNQH
GVDDEKVEFL KRLQAKTKTI TIAFGNAYSL QYFNGLKNII CTYEDNELTQ NITPQIIFGA
IKAEGKLPIT ASPSFKKGMG IETLTTSRLS YGFPQEAGMS LDTLRKIDAI IEQAIKDKAT
PGAQLLIAHK GKVVYEKQYG YQTYDEKRPV TDRTIYDIAS ITKVAATTQA VMKLYEQQRL
DINKTLGDYL PELNATNKGP LIIREVMTHQ AGLKPYIPFW EQTVKDESLN HTYINDAPGP
SGSPAIMEEE VPVALADSIW KWTLASDLRQ LPRRKQKYDY LYSDLGYTLM QRVIETIIEE
PLQDFVAREF YAPLGMWRTT FLPLEKGFYE EIAPSEVDDY FRNTIVCGNV HDQNASVMGG
ISGHAGLFST ASDLAVLMQM NMNMGEYAGK RYFNGWTVPI FTNAQNMENR RGMGWDKPIT
ATDEGPTSKF ASASTFGHTG FTGAAMWADP ANELVFVFLC NRTYPDSENF KLIEDNVRTR
IHDLVYQSIM EP
//
