ID   A0A1I0NQG4_9FIRM        Unreviewed;       336 AA.
AC   A0A1I0NQG4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Regulator of protease activity HflC, stomatin/prohibitin superfamily {ECO:0000313|EMBL:SEW03754.1};
GN   ORFNames=SAMN05421659_103297 {ECO:0000313|EMBL:SEW03754.1};
OS   [Clostridium] fimetarium.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=99656 {ECO:0000313|EMBL:SEW03754.1, ECO:0000313|Proteomes:UP000199701};
RN   [1] {ECO:0000313|EMBL:SEW03754.1, ECO:0000313|Proteomes:UP000199701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 9179 {ECO:0000313|EMBL:SEW03754.1,
RC   ECO:0000313|Proteomes:UP000199701};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOJI01000003; SEW03754.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I0NQG4; -.
DR   STRING; 99656.SAMN05421659_103297; -.
DR   OrthoDB; 9813479at2; -.
DR   Proteomes; UP000199701; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd03402; SPFH_like_u2; 1.
DR   Gene3D; 3.30.479.30; Band 7 domain; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   PANTHER; PTHR43446; MEMBRANE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR43446:SF1; MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:SEW03754.1};
KW   Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:SEW03754.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199701};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        25..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        52..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          74..269
FT                   /note="Band 7"
FT                   /evidence="ECO:0000259|SMART:SM00244"
SQ   SEQUENCE   336 AA;  37231 MW;  1E7580EBD703CC4A CRC64;
     MNLEENPKQN VIEEKELKPL NGGPVLLLLL LELTLSIVFF VLGCIFLDNE NYILGGFMLA
     IGIVAFFAFF FLIPGLHIVN PNEALVMTYF GQYYGTIKHQ GFYYTHPFAS AFNPTHRGAA
     STASANGSQT NGMQDAPTLS KKISTKTMTL SNERQKVNDV LGNPIIIGAI VIWKVADPTK
     AVFNVENYKL FLSIQCDSTI RNIARLYPYD TFEDDSDEKT LRGSSQEIAD SMKAELQQRV
     EEAGLNIQEV RITHLSYAEE IAAAMLQRQQ AVAIIAARQK IVEGAVSMVK MAIEQLGEEE
     IIVLDEERKA AMVSNLLVVL CGNKDIQPIV NTGSIY
//