ID A0A1I0P827_9FIRM Unreviewed; 550 AA.
AC A0A1I0P827;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Beta-glucuronidase {ECO:0000256|ARBA:ARBA00016205};
DE EC=3.2.1.31 {ECO:0000256|ARBA:ARBA00012761};
GN ORFNames=SAMN05421659_104237 {ECO:0000313|EMBL:SEW10437.1};
OS [Clostridium] fimetarium.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=99656 {ECO:0000313|EMBL:SEW10437.1, ECO:0000313|Proteomes:UP000199701};
RN [1] {ECO:0000313|EMBL:SEW10437.1, ECO:0000313|Proteomes:UP000199701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9179 {ECO:0000313|EMBL:SEW10437.1,
RC ECO:0000313|Proteomes:UP000199701};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; FOJI01000004; SEW10437.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0P827; -.
DR STRING; 99656.SAMN05421659_104237; -.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000199701; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000199701}.
FT DOMAIN 164..245
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 247..544
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 550 AA; 63746 MW; 3255783EF43135B4 CRC64;
MIRTFNTHKI RTSTELDGFW KIKNPQTKKE YELLVPGGAE AIMELQNFQG VLQYYREFEL
EQEQNMLFTF HGVSFWATVF LDEVEIARHY NAFTAFTAFV PSIKAGNHVL RVEVDNRFSE
ASSLHIPNDY FSYNAINRPV QMDVVGNEWI EYVHATPLEK NNGWEVQVTG QIHSLQLQQG
MMAEIEIDGI KEMTQIAVDG SFVTTIELKK ATSWSPQTPN LYFVTTHLLK DGVIVDDLIE
RTGFRSVKVS DGKILLNDKP VFLKGFCRHE DAPIWGNALP FEMMVHDIDI LKHLNCNSVR
TSHYPNDQRF LDLCDEQGIL VWEENHARGL SEQDMQNPSF KIQCKECNEE MVLQHYNHPS
IYVWGILNEC ASDTPYGREC YAEQFAQIRA LDQTRPLTFA SCKFFTDICL DLVDIVSMNL
YAGWYHDTPP QIYVKQISEW VKRVGGQNKP LIISEFGAGA IYGFHDYLGR IKWSEERQAD
LLEEQITAYL NDPDVQGLYI WQLTDCKVCE SWAEKRPKCE NNKGVVDRYR RPKMAYECVK
KLFESKDKIR
//
