ID A0A1I0PK97_9BACT Unreviewed; 442 AA.
AC A0A1I0PK97;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE RecName: Full=inositol-3-phosphate synthase {ECO:0000256|ARBA:ARBA00012125};
DE EC=5.5.1.4 {ECO:0000256|ARBA:ARBA00012125};
GN ORFNames=SAMN04487850_1827 {ECO:0000313|EMBL:SEW14790.1};
OS Prevotella aff. ruminicola Tc2-24.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=81582 {ECO:0000313|EMBL:SEW14790.1, ECO:0000313|Proteomes:UP000199373};
RN [1] {ECO:0000313|EMBL:SEW14790.1, ECO:0000313|Proteomes:UP000199373}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TC2-24 {ECO:0000313|EMBL:SEW14790.1,
RC ECO:0000313|Proteomes:UP000199373};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC Evidence={ECO:0000256|ARBA:ARBA00001911};
CC -!- PATHWAY: Polyol metabolism; myo-inositol biosynthesis; myo-inositol
CC from D-glucose 6-phosphate: step 1/2. {ECO:0000256|ARBA:ARBA00005117}.
CC -!- SIMILARITY: Belongs to the myo-inositol 1-phosphate synthase family.
CC {ECO:0000256|ARBA:ARBA00010813}.
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DR EMBL; FOIQ01000004; SEW14790.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0PK97; -.
DR Proteomes; UP000199373; Unassembled WGS sequence.
DR GO; GO:0004512; F:inositol-3-phosphate synthase activity; IEA:InterPro.
DR GO; GO:0006021; P:inositol biosynthetic process; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002587; Myo-inos-1-P_Synthase.
DR InterPro; IPR013021; Myo-inos-1-P_Synthase_GAPDH.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR11510:SF5; INOSITOL-3-PHOSPHATE SYNTHASE 1; 1.
DR PANTHER; PTHR11510; MYO-INOSITOL-1 PHOSPHATE SYNTHASE; 1.
DR Pfam; PF01658; Inos-1-P_synth; 1.
DR Pfam; PF07994; NAD_binding_5; 1.
DR PIRSF; PIRSF015578; Myoinos-ppht_syn; 1.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Reference proteome {ECO:0000313|Proteomes:UP000199373}.
FT DOMAIN 249..368
FT /note="Myo-inositol-1-phosphate synthase GAPDH-like"
FT /evidence="ECO:0000259|Pfam:PF01658"
SQ SEQUENCE 442 AA; 49718 MW; 7C8761B4A97A6D29 CRC64;
MVKTNVKPAE GKLGILVVGN GAVATTFMTG VLMTRKGLAK PVGSMTQYDK IRIGRGADKQ
YLPYKDIVPL AKLSDIVFGC WDVYPQNAYQ AAMYAEVLKE KDIEPVRDEL EKIVPMKAAF
DKNYAKRLDG DNVKDCKTRW EMVEALREDI RSFKQQNGCA RIVVLWAAST EIYVPVDEQV
HYRLSDLEAA MKADDRAHVA PSMCYAYAAL SEGAPFIMGA PNTTVDIPAM WELAEKTRMP
IAGKDFKTGQ TLVKSGFAPI IGTRCLGLSG WFSTNILGNR DGLVLDEPAN FRTKEVSKLS
TLETILKPDV QPDLYGHGND EDTQYYHKVR INYYPPRNDN KEGWDNIDIF GWMGYPMQIK
INFLCRDSIL AAPLCLDLCL LSDLAARAGR YGTQRFLSFF LKSPMHDYTQ GEEAVNHLYQ
QYTMLKNAIR EMGGYEADEE ID
//
