ID A0A1I0PTJ0_9EURY Unreviewed; 471 AA.
AC A0A1I0PTJ0;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family {ECO:0000313|EMBL:SEW17661.1};
GN ORFNames=SAMN05216285_2924 {ECO:0000313|EMBL:SEW17661.1};
OS Natrinema salifodinae.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=1202768 {ECO:0000313|EMBL:SEW17661.1, ECO:0000313|Proteomes:UP000183275};
RN [1] {ECO:0000313|Proteomes:UP000183275}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.12284 {ECO:0000313|Proteomes:UP000183275};
RA Varghese N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|RuleBase:RU003814}.
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DR EMBL; FOIS01000003; SEW17661.1; -; Genomic_DNA.
DR RefSeq; WP_049991727.1; NZ_JROF01000035.1.
DR AlphaFoldDB; A0A1I0PTJ0; -.
DR STRING; 1202768.SAMN05216285_2924; -.
DR eggNOG; arCOG01127; Archaea.
DR Proteomes; UP000183275; Unassembled WGS sequence.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04664; Nudix_Hydrolase_7; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR PANTHER; PTHR43475; METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR43475:SF1; METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF01008; IF-2B; 1.
DR Pfam; PF00293; NUDIX; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:SEW17661.1};
KW Protein biosynthesis {ECO:0000313|EMBL:SEW17661.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000183275}.
FT DOMAIN 7..142
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
FT REGION 223..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 471 AA; 50388 MW; AA73ADCE54C49CF0 CRC64;
MSDAESDASH VITAFLRNRG EVLLLRRSDA VGTYAGQWGA VSGFAEGQPD DQARIEIREE
TGLADDDVSL VRSGRPIEFA DPDLGREWVV HPYLFDCETR EIDLSEEHDA FEWVAPTETL
DAVGEDRETV PELWTAYERV APTVRSIAAD DEHGAAYLSV RALEVVRDRA GLLVAEREEF
GPDPDGERDE LAELAGRLLE ARPSMAVLRN RVNRALAEAV ADVEPDRDAA DGDAAGDQAD
TETSAPAVLE STRSNIERAL AADEDAATAA ADRIEGSIAT LSRSDTVLDA LRAGEPSRIF
VAESRPAREG IGVAERLADA TDAAVAVHTD AAVAHVLARE DVDRVVVGAD TVLPDGSVVN
KTGTRGLAVA AAREGIPVSV VAATDKVSTR EDVNLESGDR TAVYDGDAPL DVLNPTFDVT
PTDCVTEIVT ERGALDPAEI EGIADELRAL EEWRDGGPTV REATDRNPSR E
//
