ID A0A1I0PWR0_9BACT Unreviewed; 437 AA.
AC A0A1I0PWR0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Nucleobase:cation symporter-2, NCS2 family {ECO:0000313|EMBL:SEW18999.1};
GN ORFNames=SAMN04487850_2014 {ECO:0000313|EMBL:SEW18999.1};
OS Prevotella aff. ruminicola Tc2-24.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=81582 {ECO:0000313|EMBL:SEW18999.1, ECO:0000313|Proteomes:UP000199373};
RN [1] {ECO:0000313|EMBL:SEW18999.1, ECO:0000313|Proteomes:UP000199373}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TC2-24 {ECO:0000313|EMBL:SEW18999.1,
RC ECO:0000313|Proteomes:UP000199373};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; FOIQ01000005; SEW18999.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0PWR0; -.
DR Proteomes; UP000199373; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR017588; UacT-like.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR NCBIfam; TIGR03173; pbuX; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000199373};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 437 AA; 45484 MW; E51BBA8185D4AFD6 CRC64;
MTNKSNLYQL DGRVPMVQAI PFGLQHVLAM FVSNITPIII LANVVGIDSA ISATLIQNCM
IIAGIGTLIQ LYPLWRIGSR LPIVMGISFT FLSLAIFIGT SQGMGVLIGA VIIGGIVEGF
LGLLAKFWIR IISPVVAAAV VTAIGFSLLP IGANSFAGGQ GAADFGSVQN WMVGTFTLLV
CLGFQVFAKG FLRSLSVLIG LIAGYIVAAC MGMVNLSGLQ DIGIVSLPQL LPFKPEFELG
AILSIIAIYL VSATETIGDT SALCSGAIHR APTDRELGAS VSCDGFVSSV AGLFGCTPIT
SFSQNVGLAA MSGVVNRFAI ATGACIMILG GIFPIVGTVL TAIPQAVLGG CTIMMFGSIM
YAGFGMLAKC GFNNRNMVIV ALSLSVGLGF TQASEMFSIF PQIVRTVFAE NCVAVVFILA
VVLNLLLPKE EANSQSE
//
