ID   A0A1I0PYW2_9BACT        Unreviewed;       828 AA.
AC   A0A1I0PYW2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:SEW19747.1};
GN   ORFNames=SAMN04487850_2069 {ECO:0000313|EMBL:SEW19747.1};
OS   Prevotella aff. ruminicola Tc2-24.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=81582 {ECO:0000313|EMBL:SEW19747.1, ECO:0000313|Proteomes:UP000199373};
RN   [1] {ECO:0000313|EMBL:SEW19747.1, ECO:0000313|Proteomes:UP000199373}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TC2-24 {ECO:0000313|EMBL:SEW19747.1,
RC   ECO:0000313|Proteomes:UP000199373};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
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DR   EMBL; FOIQ01000005; SEW19747.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I0PYW2; -.
DR   Proteomes; UP000199373; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR032311; DUF4982.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR040605; Glyco_hydro2_dom5.
DR   InterPro; IPR006101; Glyco_hydro_2.
DR   InterPro; IPR023232; Glyco_hydro_2_AS.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR   Pfam; PF16355; DUF4982; 1.
DR   Pfam; PF18565; Glyco_hydro2_C5; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   PRINTS; PR00132; GLHYDRLASE2.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199373};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..828
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011669554"
FT   DOMAIN          44..183
FT                   /note="Glycosyl hydrolases family 2 sugar binding"
FT                   /evidence="ECO:0000259|Pfam:PF02837"
FT   DOMAIN          200..299
FT                   /note="Glycoside hydrolase family 2 immunoglobulin-like
FT                   beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF00703"
FT   DOMAIN          306..521
FT                   /note="Glycoside hydrolase family 2 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF02836"
FT   DOMAIN          641..702
FT                   /note="DUF4982"
FT                   /evidence="ECO:0000259|Pfam:PF16355"
FT   DOMAIN          726..818
FT                   /note="Glycoside hydrolase family 2"
FT                   /evidence="ECO:0000259|Pfam:PF18565"
SQ   SEQUENCE   828 AA;  93280 MW;  F20EF7B7A6E9411E CRC64;
     MRIKLLVLTM AVAATAIAQP RCEITLSDNW QFCKGSCDND GAVWKTVSVP HDWAISGPFD
     KKWDLQTVAI EQNGEKQATE KSGRSGALPW IGEGHYRRTF QIPEGYEHAE LVFDGAMAEP
     SVSINGHKAG YWAYGYNAFR IDITPYIKTG DNLLEVDLKN VEESSRWYPG AGIYRPVKLV
     LTPKSHIDMW QTCVQTLSIQ ENKALIRVSA KVENPLEEQE IFISLIDRDG QIVKTNWVKV
     PAHGDLTSTI EVEEPSLWTP ETPYLYTLGL SLVREDVDEA AGIADVVTID ETRLRFGIRT
     VSVSEEGGFQ LNGVTRKIKG VCLHHDLGPL GTAINKSALI RQIKTMKEMG CDAIRTSHNM
     PSQMQMDICD SLGMMVMAES FDMWLYPKCK NGYARFFNEW ADRDITNLVL VNRNHPSIIM
     WSIGNEIPEQ GSEKGREISC HLQELCHQLD PTRPVTQGMD RAEEALKSGF AQVMDVPGFN
     YRVHKYSKNI EQLPQGFLLG SETASTVSSR GVYKFPVEIT DNSRYASWAP TYDPTAIQTA
     DGQCSSYDVE YCSWSNLPDD DWVWQDDKPW VIGEFVWTGY DYLGEPTPYD EYWPSRSSYF
     GICDLAGLPK DRYWLYRSKW NKDEHTIHLL PHWTWDKKRR GEMTPVYCYT DYPTAELFVN
     GKSQGKISKN PASRLDRYRL RWNDVRYEPG EIKVVVYDGQ GNLAGERIIR TAGKPAKLQL
     DAWMAEGHLL KADGDDLAFV TVSLTDAQGT LIPDASDQLT FEVSGAGSFE AVCNGDATSL
     ESFTQPTMKL FHGQLVVIVR STKEAGAITL KVTDEHLNLS QAIDIPTR
//