ID A0A1I0PZG0_9FIRM Unreviewed; 567 AA.
AC A0A1I0PZG0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=EAL domain, c-di-GMP-specific phosphodiesterase class I (Or its enzymatically inactive variant) {ECO:0000313|EMBL:SEW20088.1};
GN ORFNames=SAMN05216413_1546 {ECO:0000313|EMBL:SEW20088.1};
OS Ruminococcaceae bacterium KH2T8.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae.
OX NCBI_TaxID=1855400 {ECO:0000313|EMBL:SEW20088.1, ECO:0000313|Proteomes:UP000198503};
RN [1] {ECO:0000313|EMBL:SEW20088.1, ECO:0000313|Proteomes:UP000198503}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH2T8 {ECO:0000313|EMBL:SEW20088.1,
RC ECO:0000313|Proteomes:UP000198503};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOIY01000003; SEW20088.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0PZG0; -.
DR STRING; 1855400.SAMN05216413_1546; -.
DR OrthoDB; 9762141at2; -.
DR Proteomes; UP000198503; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000198503}.
FT DOMAIN 163..294
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 303..558
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 567 AA; 65273 MW; 4AA8BE15EFF4B46E CRC64;
MTQEQTLAYY ELFEQLIDAT NDPAGFDRDK YIRLLSDICR LFRLSKGITE LYSSPAHEKA
RDGEIMCDYD DGHGDVLVLE RRVVSESMNV IIGKVYMSAD AKPLDEEEYR RVDIVLRSML
SFVARNRLIK AVERLGFYDD SGFPNMRSFT RHLQLLQHDN KLEGKTAMCF NLLHFSVINR
DIGRENGDIV ITNYTDMIRE LIGEDGILCR MGGDNFVLVC GSEDTEKIVN ILRGVPVPYD
KYKVKRVMVS ASAGIFSIPY GFELVRPGQV IDSIFTAARV ARVHSKDKIV YYDESLLQMK
DRDMWVRRLF PGALDNDEFK AFYQPKVDVE TGKIVGAEAL CRWIQQGKIV PPMEFIPILE
QNTDICILDF HMLDIVCRDI RRWLDEGRNA VRVSVNLSRK HLVDVDLIKH ILEIIDRNRV
PHEYIEVELT ETTTDVEFRD LRRVVIGLQE AGVHVSVDDF GMGYSSLNLI RELPWDVLKI
DKCFVPTDEE TDDGITSKMF RHVVNMAQDI GLKCIAEGVE TEKQLGLLKI NKCDIAQGYY
FDKPLPVNEF EERLDKGFYD VSWVKKN
//
