ID A0A1I0Q3Z8_9RHOB Unreviewed; 797 AA.
AC A0A1I0Q3Z8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
DE AltName: Full=DNA 3'-5' helicase II {ECO:0000256|ARBA:ARBA00034923};
GN ORFNames=SAMN04488515_1650 {ECO:0000313|EMBL:SEW21647.1};
OS Cognatiyoonia koreensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Cognatiyoonia.
OX NCBI_TaxID=364200 {ECO:0000313|EMBL:SEW21647.1, ECO:0000313|Proteomes:UP000199167};
RN [1] {ECO:0000313|EMBL:SEW21647.1, ECO:0000313|Proteomes:UP000199167}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17925 {ECO:0000313|EMBL:SEW21647.1,
RC ECO:0000313|Proteomes:UP000199167};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
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DR EMBL; FOIZ01000001; SEW21647.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0Q3Z8; -.
DR STRING; 364200.SAMN04488515_1650; -.
DR OrthoDB; 9806690at2; -.
DR Proteomes; UP000199167; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR CDD; cd18807; SF1_C_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000199167}.
FT DOMAIN 31..311
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT DOMAIN 312..586
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51217"
FT BINDING 52..59
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 797 AA; 88721 MW; C1FFFC8FDED6E562 CRC64;
MSSFSEEDAF EAASVPLSQR AMVGRGAPYL DELNPAQREA VQTLDGPVLM LAGAGTGKTK
ALTSRIAHLL TTGTARPHEI LAVTFTNKAA REMKMRVGRL LGEAVEGMPW LGTFHAISVK
LLRRHAELVG LKSNFTILDT DDQLRLLKQL VVADDIDEKR WPPRMLAGII DGWKNKALTP
DKVPVAESGA FDHKGIDLYA AYQRRLLDLN ACDFGDLLLH VVTIFQTHPD VLEQYQRWFR
YILVDEYQDT NVAQYLWLRL LAGGHKNICC VGDDDQSIYG WRGAEVGNIL RFEKDFPGAH
VVRLEQNYRS TGHILGAAGG VISANKGRLG KTLFTEGDDG EKVRLIGHWD GEEEARWIGE
EVEALQRGTR GLSPYSLDHM AILVRASHQM RAFEDRFLTI GLPYRVIGGP RFYERMEIRD
AMAYFRLAVS QDDDLAFERI VNTPKRGLGD KAVQTIQRTA RSNGVSLVEG ARLVVQGKLL
GGKGLKELAL LVDGLDRWHA QVRAEEDTHV ELAEMILDES GYTGFWQNDK TPEAPGRLEN
LKELVKALEN FENLQGFLEH VSLIMDNETE QEGEKVSIMT LHAAKGLEFP CVFLPGWEDG
LFPSQRSMDE SGMKGLEEER RLAYVGITRA EEICTISFAA NRRVYGQWQS SMPSRFIDEL
PEDHVEVLTP PGLYGGGYGA AGMAASANPR VQEMMGSDLH QKAAEANVYN SPGWKRLQSR
SQQRGMAQPS EARNMTIDLD AVSAFTEGDR VFHQKFGYGE VMGIEGEKLL IEFDKAGTKN
VIAKFIVNAD AADDVPF
//
