ID   A0A1I0QU82_9EURY        Unreviewed;       473 AA.
AC   A0A1I0QU82;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Alpha-galactosidase {ECO:0000313|EMBL:SEW31198.1};
GN   ORFNames=SAMN05216285_3966 {ECO:0000313|EMBL:SEW31198.1};
OS   Natrinema salifodinae.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC   Natrialbaceae; Natrinema.
OX   NCBI_TaxID=1202768 {ECO:0000313|EMBL:SEW31198.1, ECO:0000313|Proteomes:UP000183275};
RN   [1] {ECO:0000313|Proteomes:UP000183275}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.12284 {ECO:0000313|Proteomes:UP000183275};
RA   Varghese N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540;
CC         Evidence={ECO:0000256|ARBA:ARBA00001911};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 4 family.
CC       {ECO:0000256|ARBA:ARBA00010141}.
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DR   EMBL; FOIS01000005; SEW31198.1; -; Genomic_DNA.
DR   RefSeq; WP_049989948.1; NZ_JROF01000010.1.
DR   AlphaFoldDB; A0A1I0QU82; -.
DR   STRING; 1202768.SAMN05216285_3966; -.
DR   eggNOG; arCOG06070; Archaea.
DR   OrthoDB; 92947at2157; -.
DR   Proteomes; UP000183275; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.1820.10; AglA-like glucosidase; 1.
DR   InterPro; IPR019802; GlycHydrolase_4_CS.
DR   InterPro; IPR001088; Glyco_hydro_4.
DR   InterPro; IPR022616; Glyco_hydro_4_C.
DR   InterPro; IPR015955; Lactate_DH/Glyco_Ohase_4_C.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR32092; 6-PHOSPHO-BETA-GLUCOSIDASE-RELATED; 1.
DR   PANTHER; PTHR32092:SF2; ALPHA-GALACTURONIDASE; 1.
DR   Pfam; PF02056; Glyco_hydro_4; 1.
DR   Pfam; PF11975; Glyco_hydro_4C; 1.
DR   PRINTS; PR00732; GLHYDRLASE4.
DR   SUPFAM; SSF56327; LDH C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS01324; GLYCOSYL_HYDROL_F4; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183275}.
FT   DOMAIN          216..438
FT                   /note="Glycosyl hydrolase family 4 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11975"
SQ   SEQUENCE   473 AA;  52966 MW;  59D3A636B07AB2CE CRC64;
     MHQLGSRSSD GTPRMKIGYV GGGSQGWAHT LINDLAQCED VAGTVALYDV DYEAAAANAK
     LGNRVVDRAD ADGDWTFEAV RELDDALSDA DFVVCSIQDP PEETFVHDID LPKRYGIHQP
     VADTVGPGGT LRAMRAIPQY REIAATVRER CPDAWVINYT NPMTVCTRTL YEEFPEIKAI
     GLCHEVFQLQ ELFAEIAERH LEEADDVNRE EIHVNVKGIN HFTWIDEARW RGRDLYRFLD
     DELEARKPLN DFEPGAMADA SYWVTNYRVA FDLYDRFGAL PAAGDRHLVE FVPWYLDLDD
     PEELHRWGIR FTPSSARRPD EGPSQTERYL SGEDAFELSE SGEELVDIVR ALLGLEPVET
     HLNYPNEGQM ADLPEGAVVE TNALLTGDDV SPLTAGSLPD EVRSMVETHV TNQKTLVEAG
     FDGDLDRAFR AFLNDPLVTI DRAAAAALFT DLVEREREYL GAWNLEKSEV LSS
//