ID A0A1I0RF41_9BACT Unreviewed; 451 AA.
AC A0A1I0RF41;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Precorrin-8X methylmutase {ECO:0000313|EMBL:SEW39277.1};
GN ORFNames=SAMN05428988_5041 {ECO:0000313|EMBL:SEW39277.1};
OS Chitinophaga sp. YR573.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Chitinophaga.
OX NCBI_TaxID=1881040 {ECO:0000313|EMBL:SEW39277.1, ECO:0000313|Proteomes:UP000198758};
RN [1] {ECO:0000313|EMBL:SEW39277.1, ECO:0000313|Proteomes:UP000198758}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YR573 {ECO:0000313|EMBL:SEW39277.1,
RC ECO:0000313|Proteomes:UP000198758};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
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DR EMBL; FOJF01000002; SEW39277.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0RF41; -.
DR STRING; 1881040.SAMN05428988_5041; -.
DR OrthoDB; 9772960at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000198758; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd11646; Precorrin_3B_C17_MT; 1.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR006363; Cbl_synth_CobJ/CibH_dom.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR NCBIfam; TIGR01466; cobJ_cbiH; 1.
DR PANTHER; PTHR47036; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR47036:SF1; COBALT-FACTOR III C(17)-METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF02570; CbiC; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 2..211
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
FT DOMAIN 252..444
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 451 AA; 49898 MW; 8E0CCA117DF1D65F CRC64;
MKLSVVGIGP GGQDYILPFA QQVLADADIV IGYSYYFQFI QHLLKPGAVA VGKDLTEEEA
RAELAVNSCE PGKHVVVISS GDAGIYAMAS LVYEYASKRP DKELDLQTVP GISAFIASAG
KLGAPLGHDF CCISLSDLMT PWTTIEKRIF AAATGDFVTS LYNPRSKKRY WQLERFKEIF
LEHRDPETPV AIIRQVTRPE EHITITTLQE FDTSLVDMFS LVMVGNSQTY QFKNFLVTPR
GYLARKPQTG EEIQNESFRQ ITEQLHRDDV SVADQWAIIR CIHTTADFEY EDLYISNKDA
ISRWHEYLVN GGTVVTDVTM VQSGITKEFI SRYNVNVYCY LNDPETIPLA EKEGLTRSQA
GMRIAIAKHP EALFVVGNAP TALFELCDQF PGFNPAGIIG APVGFVNVVE SKLKLQAMKQ
VPYVIIKGRK GGSNVAASIV NAAFTVNTLG S
//
