ID   A0A1I0TGH3_9SPHI        Unreviewed;       465 AA.
AC   A0A1I0TGH3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Glucosylceramidase {ECO:0000313|EMBL:SFA50840.1};
GN   ORFNames=SAMN04488511_109191 {ECO:0000313|EMBL:SFA50840.1};
OS   Pedobacter suwonensis.
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=332999 {ECO:0000313|EMBL:SFA50840.1, ECO:0000313|Proteomes:UP000198836};
RN   [1] {ECO:0000313|Proteomes:UP000198836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18130 {ECO:0000313|Proteomes:UP000198836};
RA   Varghese N., Submissions S.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382, ECO:0000256|RuleBase:RU361188}.
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DR   EMBL; FOJM01000009; SFA50840.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I0TGH3; -.
DR   STRING; 332999.SAMN04488511_109191; -.
DR   OrthoDB; 9806701at2; -.
DR   Proteomes; UP000198836; Unassembled WGS sequence.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR033452; GH30_C.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF02055; Glyco_hydro_30; 1.
DR   Pfam; PF17189; Glyco_hydro_30C; 1.
DR   PRINTS; PR00843; GLHYDRLASE30.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU361188};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361188};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..465
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011526253"
FT   DOMAIN          68..401
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   DOMAIN          404..463
FT                   /note="Glycosyl hydrolase family 30 beta sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF17189"
SQ   SEQUENCE   465 AA;  50898 MW;  CC3D57B0796B7B09 CRC64;
     MLITKSIGLL IGCAFTFSVM AQSQPQVWLT KADRTALFTR QTAGLRLSAA KKKQPVIAIN
     DKKTFQSIDG FGYALTGGSA QHIVKMSAPA RAALLRELFA TDGNNIGVSY IRLSIGASDL
     NEKVFSYNDI PEGQTDVEQA KFDLGPDKAD VIPVMKEILA INPRIKIMGS PWSPPLWMKT
     TYDARGGMLK PEYYAAYAKY FVRYVQEMKK EGISIDAITV QNEPLHPGNN PSLFMAAPDQ
     ALFVKQFLGP AFAKASIKTK IIVYDHNADR PDYPISILDD PEARKYIDGS AFHLYGGKIE
     ALSDVHDAHP DKNIYFSEQM VVEQPDATTI DIINPVARLI IGATRNWARN VLEWNLAADP
     ENKPYTDRGG CSMCQGAVTI NGDHYSRNLA YFSIAHAAKF VRPGSVRVAS NEPEGLANVA
     FKTPEGKHVL IVANTGKATA AFNISLKGKS YAAALDKGAV ATYIW
//