ID A0A1I0U9G2_9SPHI Unreviewed; 649 AA.
AC A0A1I0U9G2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SAMN04488511_12913 {ECO:0000313|EMBL:SFA60493.1};
OS Pedobacter suwonensis.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=332999 {ECO:0000313|EMBL:SFA60493.1, ECO:0000313|Proteomes:UP000198836};
RN [1] {ECO:0000313|Proteomes:UP000198836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18130 {ECO:0000313|Proteomes:UP000198836};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; FOJM01000029; SFA60493.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0U9G2; -.
DR STRING; 332999.SAMN04488511_12913; -.
DR OrthoDB; 1006965at2; -.
DR Proteomes; UP000198836; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR026876; Fn3_assoc_repeat.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF13287; Fn3_assoc; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PIRSF; PIRSF001093; B-hxosamndse_ab_euk; 2.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..649
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011772713"
FT DOMAIN 41..174
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 179..534
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 369
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 649 AA; 73325 MW; 3FBDA3250C6B4010 CRC64;
MKKLFLIISC CFFAANISAQ NIVTETEIGA AESEVVPTPI AIIPEPVSLV KKAGTFTLPE
NIIVQAAKST ELKQSINYLS DRITTATGKF VSSVSNSSHP TIKLILNTQE DVQLGKEGYK
LNVNPTQVVI TANQPAGIFY GIQSLLQLFP AEIESKELVN GIKWKAPCVD VIDYPKLGWR
GLMFDVARHF FTKQEVKQFI DGMVRYKFNL LHLHLADDEG WRIEIKGLPK LTEIGAWSVK
KTGTFGDFTP PAPDEPRTYG GFYTQDDIKE LVQYAQERFV NILPEIDVPG HSLAIIASYP
ELSCTPEAIN YKVRSGEKIM DWSRGAPPTA LVDNTLCPAN EKVYVFLDSV LTQVANLFPF
EYIHMGGDEA PHNFWEKNDQ IKALMVREGL KTMPQVQAYF EKRVEQIVIS KGKKFMGWDE
ILEGGVSPTA AVMSWRGMKY GIQAANDKHN VVMSPTDFAY LDYMQADAIT EPKVYASLRL
NKAYQFNPVP ASVNAKYIIG AQANLWTEQI FTFRQVEYML YPRAFAIAES IWSPIDKKNW
TNFVDRTQQH FKRLDLAEIK YSPAIYDPIF TVKRSADKQL MVELTTEIDG LDIYYSFDNS
TPDRFYPKYT AALQVPKDAS MLRVITYRGK QPIGRLISMP VADLQKRAR
//
