ID   A0A1I0VJD7_9BACT        Unreviewed;       458 AA.
AC   A0A1I0VJD7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family {ECO:0000313|EMBL:SFA76432.1};
GN   ORFNames=SAMN04489723_101224 {ECO:0000313|EMBL:SFA76432.1};
OS   Algoriphagus aquimarinus.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC   Algoriphagus.
OX   NCBI_TaxID=237018 {ECO:0000313|EMBL:SFA76432.1, ECO:0000313|Proteomes:UP000198790};
RN   [1] {ECO:0000313|EMBL:SFA76432.1, ECO:0000313|Proteomes:UP000198790}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23399 {ECO:0000313|EMBL:SFA76432.1,
RC   ECO:0000313|Proteomes:UP000198790};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. RsmB/NOP family. {ECO:0000256|PROSITE-ProRule:PRU01023}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FOKK01000001; SFA76432.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I0VJD7; -.
DR   STRING; 237018.SAMN04489723_101224; -.
DR   OrthoDB; 9810297at2; -.
DR   Proteomes; UP000198790; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0001510; P:RNA methylation; IEA:InterPro.
DR   Gene3D; 2.30.130.60; -; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR031341; Methyltr_RsmF_N.
DR   InterPro; IPR049560; MeTrfase_RsmB-F_NOP2_cat.
DR   InterPro; IPR001678; MeTrfase_RsmB-F_NOP2_dom.
DR   InterPro; IPR027391; Nol1_Nop2_Fmu_2.
DR   InterPro; IPR023267; RCMT.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR22807:SF30; 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR22807; NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING; 1.
DR   Pfam; PF01189; Methyltr_RsmB-F; 1.
DR   Pfam; PF17125; Methyltr_RsmF_N; 1.
DR   Pfam; PF13636; Methyltranf_PUA; 1.
DR   PRINTS; PR02008; RCMTFAMILY.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51686; SAM_MT_RSMB_NOP; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW   ProRule:PRU01023}; Reference proteome {ECO:0000313|Proteomes:UP000198790};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU01023};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01023};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW   ProRule:PRU01023}.
FT   DOMAIN          1..298
FT                   /note="SAM-dependent MTase RsmB/NOP-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51686"
FT   ACT_SITE        230
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         109..115
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         133
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         160
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
FT   BINDING         177
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01023"
SQ   SEQUENCE   458 AA;  52698 MW;  13EF1F97D10D657B CRC64;
     MPATKLPKDF ESQMLELLGK AEFEQFKQAI NNPSRTSIRL NSDKDFSLSW ANTPIPWSKT
     GFFLEERPSF TLDPAIHAGA YYVQEASSIF IEHLLNSLAI PKGIYLDLAA APGGKSTLLS
     AYLGNEGMLV ANEVIQPRAQ ILKENIIKWG LGNTVVTNND PDHFAPLQGF FDLVLVDAPC
     SGEGMFRKDP QARDEWSLDN VQLCSARQKR IMDQAGALVK ADGYLVYSTC TFNEQENENM
     IRFLTEEFSY EPVRIPLDAS WNIKETEVDA DGKTFYGYRF FPHLVEGEGF FITVWKRSSE
     AYIQEPKRVK DFKHPFLKEV FNRESSILDE ELGFDGTGKY FTLNDSYFRI SKDWTLHFQK
     LSLHLSLKYF GVELGKKQKK DWIPNHEWAL STLPKKDFPA HELSESEAIE FLRKNDIEIP
     DLPIGWVLIT YKELPLGWIK NLGNRVNNYY PKEWRIRM
//