ID   A0A1I0VKK7_9CELL        Unreviewed;       667 AA.
AC   A0A1I0VKK7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Cell division protein FtsI (Penicillin-binding protein 3) {ECO:0000313|EMBL:SFA76862.1};
GN   ORFNames=SAMN05421867_101455 {ECO:0000313|EMBL:SFA76862.1};
OS   Cellulomonas marina.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Cellulomonadaceae;
OC   Cellulomonas.
OX   NCBI_TaxID=988821 {ECO:0000313|EMBL:SFA76862.1, ECO:0000313|Proteomes:UP000199012};
RN   [1] {ECO:0000313|EMBL:SFA76862.1, ECO:0000313|Proteomes:UP000199012}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.6945 {ECO:0000313|EMBL:SFA76862.1,
RC   ECO:0000313|Proteomes:UP000199012};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
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DR   EMBL; FOKA01000001; SFA76862.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I0VKK7; -.
DR   STRING; 988821.SAMN05421867_101455; -.
DR   OrthoDB; 9789078at2; -.
DR   Proteomes; UP000199012; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.450.330; -; 1.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000313|EMBL:SFA76862.1};
KW   Cell division {ECO:0000313|EMBL:SFA76862.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199012};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        102..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          147..299
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          343..643
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
FT   REGION          1..85
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          360..381
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..50
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..381
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   667 AA;  67929 MW;  D40604CA013AF421 CRC64;
     MTTTTPRPAR RAPGATATPG GAARATTTSA TTTSATATRG ATTSTAVRPG VVGTNRRPAS
     GAGNARPARA GAGGGGGGAG GRGGRRPGAL GPVAADARGR TAFLTVLVLA LLAVFAGRLV
     WVQVVVGPAR AEEALASRLT TRTEVLGTRG QITDADGVAL ATSVERYVVW VNQHQVAEFR
     GSDEAPEGAA GVAQLLAPLL DADVAELGGR LVGEAGYKVL QKDVLPEIAR EIRSLGLPGI
     GVDMVPDRVY PNGTLAGNVV GFVNSSDQGV AGLEAALDGT LTGEAGWEQY ERGRMGQAIP
     GGYSEGDPAR DGLSVRTTIV SDIQWKAQAA LDAQVAATGS DSGTVVVMDP RTGAVLALAD
     SGSIDPNSPG GSTGSLTPSV SDVFEPGSTG KVVTMAAALE QGITTPTDQY EVPYTYTTEN
     GQTFKDSHEH ELQRLTTTGV LAESSNTGTV MIGQRLSEPT REEYLRRFGF GARTGIELPG
     ESAGRLLPAE EWDGRSQYAV LFGQALSVTA VQATSVFATI ANGGVRVAPH LVAGTTDEDG
     TFTPAAPAAS TQVVSAETAG TVLSMLESVV DDGTGGSAAI EGYRVAGKTG TAQNWVDGVQ
     GITASFIGVA PVDDPRLVVS VILHNPRTSE WGGTVAAPVF QDVTRYALGE LGVAPSGTAP
     TLYPTTW
//