ID A0A1I0XD57_9FIRM Unreviewed; 585 AA.
AC A0A1I0XD57;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Radical SAM superfamily enzyme YgiQ, UPF0313 family {ECO:0000313|EMBL:SFA98962.1};
GN ORFNames=SAMN05216249_106103 {ECO:0000313|EMBL:SFA98962.1};
OS Acetitomaculum ruminis DSM 5522.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Acetitomaculum.
OX NCBI_TaxID=1120918 {ECO:0000313|EMBL:SFA98962.1, ECO:0000313|Proteomes:UP000198838};
RN [1] {ECO:0000313|EMBL:SFA98962.1, ECO:0000313|Proteomes:UP000198838}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5522 {ECO:0000313|EMBL:SFA98962.1,
RC ECO:0000313|Proteomes:UP000198838};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; FOJY01000006; SFA98962.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0XD57; -.
DR STRING; 1120918.SAMN05216249_106103; -.
DR OrthoDB; 9801424at2; -.
DR Proteomes; UP000198838; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR025288; DUF4080.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR PANTHER; PTHR43409:SF18; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF13311; DUF4080; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000198838}.
FT DOMAIN 1..132
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 169..399
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 585 AA; 68814 MW; CEE9D20CC205B2A3 CRC64;
MKILLVGVNA KYIHTGLAIR SLKKYSGFKE VELCEYTINH EKGFVISEIF KKKADVLAFS
CYIWNINYIY EICSDLSKIL PETDIWLGGP EVSFDAEEVL KNHPYLKGVM RGEGEEIFKE
LSSFYVKKET DLESIKGITY KEKDEIIKNP DMPLLNMDLL PFCYDEEEFN DKKIMYYEGS
RGCPFSCSYC LSSLDKKVRF KSIDLVKKEL KIFIEKKVPQ VKFVDRTFNC SKKYTMAVWK
FLVENDKGIT NFHFEIEADI LDDEEIELIN SMRPGLIQLE IGVQSTNDNT IKAINRRVEF
SKIKKAVEKI AKNNNVHQHL DLIAGLPFEG FESFRKSYND VYSLKPNQLQ LGFLKVLKGS
KMHEMAKEYG IKYQNKAPYE VLMTDFLSYD EIIKIKLVEE MTEVYYNSHQ FDTCLATINP
QNTFDFFLNL GKYYDDKGLL EIKHKRVSRY EILIDYVKNE ALAEEKLLLE AADFDLYLRE
NMKTRPAFSK SYSNEEKEII KEFYKKEAME HNLLKDYEKM DYKQLMRMTH IGIYSNDFTR
ADADFKLDNE KKYYILFDYK NRSEIDYSAR VYLINDLLKG ETNVI
//
