ID   A0A1I0XNJ2_9ACTN        Unreviewed;       523 AA.
AC   A0A1I0XNJ2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 {ECO:0000256|ARBA:ARBA00040298};
GN   ORFNames=SAMN05192575_102492 {ECO:0000313|EMBL:SFB01523.1};
OS   Nocardioides alpinus.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=748909 {ECO:0000313|EMBL:SFB01523.1, ECO:0000313|Proteomes:UP000199113};
RN   [1] {ECO:0000313|EMBL:SFB01523.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.10697 {ECO:0000313|EMBL:SFB01523.1};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable oxidoreductase that may play a role as regulator of
CC       mitochondrial function. {ECO:0000256|ARBA:ARBA00037217}.
CC   -!- SUBUNIT: Interacts with COX5B; this interaction may contribute to
CC       localize PYROXD2 to the inner face of the inner mitochondrial membrane.
CC       {ECO:0000256|ARBA:ARBA00038825}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC       {ECO:0000256|ARBA:ARBA00004305}.
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DR   EMBL; FOKC01000002; SFB01523.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I0XNJ2; -.
DR   STRING; 748909.SAMN05192575_102492; -.
DR   OrthoDB; 9774675at2; -.
DR   Proteomes; UP000199113; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR10668; PHYTOENE DEHYDROGENASE; 1.
DR   PANTHER; PTHR10668:SF103; PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
FT   DOMAIN          20..300
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
SQ   SEQUENCE   523 AA;  54952 MW;  68881A7051320FFF CRC64;
     MNSGSSSYDV VVVGGGHNAL VSAAYLARAG LSVLVLERLD HTGGAAVSVE PFAGQPARLS
     RYSYLVSLMP EQLMADLGLD IRLASRTTAS YTPWTRSERS GGLLVERPEG EATRASFREL
     TGSDEEYAAW QDFYAEVGRL AEVVSPTLMQ PLPLERDVRA LADERIWNDV VTQPLGHAIT
     SRFTDDTVRG VVATDALIGT FASMDDPSLI QNRCFLYHLI GNGTGEWRVP IGGMGAVTDA
     LAKAAVDAGA EILTGAGVSA ITPGADGAEV TWHDSTGQHA VTARRVLSGV APWVLRILLG
     EGEDEDNKPS GSQLKINFLL DRLPALASGA DPATAFAGTL HLAEDYTQLE QAYAAAAGGA
     VPDPMPGEVY CHSLSDPSIL GDRAGSAHTL TYFGLHTPAA LFDADPGARD VAIGRALASL
     NAVLAEPLED CLATDADGHP CIETKIPQDI EKDLAMPGGH IFHGDLEWPW ANNRARLDTP
     AQQWGVQTEH DSVLLCGSGA RRGGAVSGLG GHNAAQAVLA ELG
//