ID A0A1I0YSI7_9BACL Unreviewed; 1010 AA.
AC A0A1I0YSI7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=HEAT repeat-containing protein {ECO:0000313|EMBL:SFB15786.1};
GN ORFNames=SAMN05216312_104102 {ECO:0000313|EMBL:SFB15786.1};
OS Cohnella sp. OV330.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Cohnella.
OX NCBI_TaxID=1855288 {ECO:0000313|EMBL:SFB15786.1, ECO:0000313|Proteomes:UP000198686};
RN [1] {ECO:0000313|EMBL:SFB15786.1, ECO:0000313|Proteomes:UP000198686}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OV330 {ECO:0000313|EMBL:SFB15786.1,
RC ECO:0000313|Proteomes:UP000198686};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
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DR EMBL; FOKE01000004; SFB15786.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I0YSI7; -.
DR Proteomes; UP000198686; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004155; PBS_lyase_HEAT.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR12697:SF5; DEOXYHYPUSINE HYDROXYLASE; 1.
DR PANTHER; PTHR12697; PBS LYASE HEAT-LIKE PROTEIN; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13646; HEAT_2; 1.
DR SMART; SM00100; cNMP; 1.
DR SMART; SM00567; EZ_HEAT; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000198686};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 54..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 876..980
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 1010 AA; 109413 MW; 3FAB0B0716432C6D CRC64;
MAQALGRLGV RAEDRRKLRL MTPIFLICGI AEALTYNGFI TLFSQRFGSE YLPYLYTAEA
FILPLEAWFM SWLAMKLSKP ALMKTMYAVM TAILLADTGV LAALKLADLD ARWFYPVLFL
TSSFVVRQQT VLLWSLAVDV CPTQQAKRLM PLFVSGATLG GAAGGLATQM LSPLGAEWVY
GLGPLLLIAA SFNYRKAIVQ YLVPLALKAQ AAAEDEGASS FIYMKRTFRS PFLLGVMGLM
TLMPALYYLA EFLFLNTAHA SYPDEQQFAR MFGIVSTLLF LLAFAVQLVS GKLVAWFGAS
GMLVAIAAAY AAAFGLSAVL LGSETAAVTA AAGAYMLTNV LIFYSAEPSY QLFYKTLPMQ
HRDGYRYAAQ GLASFFGILL GAGLQSLHKA AGFSFPILAA VGAGAALLLT ALAWTVRRLY
MRELVRGVQT LGLDDRELMD SYREFFSNTK AMGAVLTLLR DEQEGVRQIA ADIVGRTQDE
RYVPELLELL GDESPGVRTA ALRAMKLTGA DLQALVRIGA VLEDEDPAVR AEGVRQMAQM
KHLSSQAFFF LRMKLLDPHP AVVAEAVKAM YALESESSYE ACFEAIERLL GQGGEPAAHV
CGVVAELRLE RFGESVERLL QDTHPSVRLA ATSCLGKLGA AHVVPQLLER LPAGDQELMR
VTEQALIDMG HLSIEPLLSA LPGAHAQIWR VAIGALAVLL PEDDIRGRLT DEALRRMGGL
DKVAGYASAF RAVGREELAE LAALRFNGQR QRILEGVWSL LVRLTDEQVV ASIRRALADA
DDETKSSGLE VLAEGAGDRR LAQRLSVVLQ TDYDDRGRLS ATIEEARTAL EHASRSADDW
WPEMAAEAGR ERGGQVEAQG ALGRLGKVIY LKNVPFFADL TLEELGLIAG IASERVFEDG
EALLLRGSTS DALYVIVDGN VELTSVTAAG LEATLGVLGA GEVCGATSAL DESASTVSAH
ALLGDVRALG LQREALTRLV RLYPDIGLGL LRASLARVRL LEEMLMRIDS
//
