ID A0A1I1C8Y7_9BACT Unreviewed; 582 AA.
AC A0A1I1C8Y7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Endoglucanase {ECO:0000256|RuleBase:RU361166};
DE EC=3.2.1.4 {ECO:0000256|RuleBase:RU361166};
GN ORFNames=SAMN04489723_12410 {ECO:0000313|EMBL:SFB58486.1};
OS Algoriphagus aquimarinus.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae;
OC Algoriphagus.
OX NCBI_TaxID=237018 {ECO:0000313|EMBL:SFB58486.1, ECO:0000313|Proteomes:UP000198790};
RN [1] {ECO:0000313|EMBL:SFB58486.1, ECO:0000313|Proteomes:UP000198790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23399 {ECO:0000313|EMBL:SFB58486.1,
RC ECO:0000313|Proteomes:UP000198790};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC Evidence={ECO:0000256|RuleBase:RU361166};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 9 (cellulase E) family.
CC {ECO:0000256|PROSITE-ProRule:PRU10059, ECO:0000256|RuleBase:RU361166}.
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DR EMBL; FOKK01000024; SFB58486.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1C8Y7; -.
DR STRING; 237018.SAMN04489723_12410; -.
DR OrthoDB; 9808897at2; -.
DR Proteomes; UP000198790; Unassembled WGS sequence.
DR GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR CDD; cd02850; E_set_Cellulase_N; 1.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR004197; Cellulase_Ig-like.
DR InterPro; IPR001701; Glyco_hydro_9.
DR InterPro; IPR033126; Glyco_hydro_9_Asp/Glu_AS.
DR InterPro; IPR018221; Glyco_hydro_9_His_AS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR22298; ENDO-1,4-BETA-GLUCANASE; 1.
DR PANTHER; PTHR22298:SF29; ENDOGLUCANASE; 1.
DR Pfam; PF02927; CelD_N; 1.
DR Pfam; PF00759; Glyco_hydro_9; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS00592; GH9_2; 1.
DR PROSITE; PS00698; GH9_3; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|PROSITE-ProRule:PRU10059};
KW Cellulose degradation {ECO:0000256|RuleBase:RU361166};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|PROSITE-
KW ProRule:PRU10059};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU10059};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326,
KW ECO:0000256|PROSITE-ProRule:PRU10059};
KW Reference proteome {ECO:0000313|Proteomes:UP000198790}.
FT DOMAIN 31..109
FT /note="Cellulase Ig-like"
FT /evidence="ECO:0000259|Pfam:PF02927"
FT DOMAIN 125..573
FT /note="Glycoside hydrolase family 9"
FT /evidence="ECO:0000259|Pfam:PF00759"
FT ACT_SITE 510
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10059"
FT ACT_SITE 552
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10060"
FT ACT_SITE 561
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10060"
SQ SEQUENCE 582 AA; 64948 MW; 9E9FD28555C99936 CRC64;
MKSKNLIFFG LLLIQWACKA PMIDANLPVD ESIRLNQIGF YPDQQKIAII LNHEDAEDFV
IWDMDKKDIV FEGKLAKQTT KTLSGQNTRV ADFSEFSQTG KFVLVLTGVS KSYPFEIAEQ
VNEQLGKASI KAFYFQRAGI ELDKAHAGIW ARQPGHPDDQ VMIHPSAASD TRKAGHLVSS
PFGWYDAGDY NKYVVNSGIT VGTLLSLYED YPSYFQKLEL NIPESGNQIP DLLDEIRWNL
DWMITMQDAG DGGVYHKLTT AKFEGMVEPH LAVSQRYMVA KSTTATLDFA AVMAQASRVY
KSYYPEESVT YLKAAEKAWN WAKVNPEVLY NQNVMNEAFD PDVVTGAYGD FSAADERIWA
ASELFVTTHN LIYWEELADA DQSFKLPSWN QVSWLGYYSL LRHQDSITLF PQEWMAVLKI
NLLSGARTQL EGVASTAFQS PLETNATNFK WGSNAVAANQ GILLLYAYKQ SGERAFLDGA
FDNLDYILGR NATGYSYVTG FGSKTPLHPH HRLAVSRPDL PPLPGFIVGG PNPGQQDGCT
YSSSFADESY TDESCSYASN EIAINWNAPF AYLANSLEAI NQ
//
