ID A0A1I1DFM0_9BURK Unreviewed; 1837 AA.
AC A0A1I1DFM0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN05216321_101282 {ECO:0000313|EMBL:SFB71323.1};
OS Cupriavidus sp. OV038.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=1855313 {ECO:0000313|EMBL:SFB71323.1, ECO:0000313|Proteomes:UP000199583};
RN [1] {ECO:0000313|EMBL:SFB71323.1, ECO:0000313|Proteomes:UP000199583}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OV038 {ECO:0000313|EMBL:SFB71323.1,
RC ECO:0000313|Proteomes:UP000199583};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FOKX01000001; SFB71323.1; -; Genomic_DNA.
DR Proteomes; UP000199583; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 1..277
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1466..1538
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1541..1590
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1617..1833
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 1581..1608
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1837 AA; 203352 MW; 36B1E8374CE1E84D CRC64;
MGNSQSPQIL WQDGEHVFCR GQRPGNDGAD IVLIVRPAAD YPSSASLDRL AHEFRLKDEL
DSAWAVRPLE LLREDGRTSL VLEDPGGEPL ELLLGAPMET GRVLRFAAGI AAALGQFHQR
GLVHKDFKPA HVLVNGTDGR ARLTGFGIAS RLPREHQAPE PPETIAGTLA YMAPEQTGRM
NRSIDSRSDL YSLGVVIYQM LTGVLPFSAS EPMEWVHCHI ARKPMPPSER LTSIPAPLCQ
IVMKLLAKTA EERYQTAAGV EQDLRRCLAA WESHRQIDGF PLGEHDTPDR LVIPEKLYGR
EREVNRLLAA FNRVITRGAP ELVLVSGYSG IGKTAVVNEL HKVLVPPRGL FAAGKFDQYK
RDIPYSTLVQ AFQSLVRPLL GKRDAELASW RAALLEALEP NARLMTDLIP ELKLIIGEQP
PVPELEPQQA QRRFQLVLRR FIGVFARPEH PLALFLDDLQ WLDTATLDLL EDVLARSDLQ
HLMVIGAYRD NEVDAAHPLT HKLQAIRSAR GTVEEITLAP LGREHLGQLI ADAVCCDTTR
VASLAQLVHE KTAGNPFFVI QFLYALAEER LFHFDHDTKG WSWHLDRIHA KGYTDNVVDL
MVGKLSRLPS ETQQALQQLA CLGNIAEITM LSTVLVIPEK EVHAVLWEAV RLELVERLEG
AYRFIHDRVQ EAAYSLIPKA MRAEVHLRIG RLLVARTPIG QQEAAIFEIV NQLNRGAALI
TAQAERDQLA GLNLMAGKRA KGSTAYASAL TYLNIGVALL GEDSWERQHE MLFALELNRA
ECTFLTGELS VADEELAALS GHAATTVEQA IVACLHMDVC LVLDQSSRAI NVGLNCLRHF
GIDWSPHPDG DEVRREYGRI GSALEDREIE ALIDMPLMED PASLATVDVL MKLWTPALYT
DENLASLTIC KAVGLSLEHG NCDASCFAYV ILIRIAGPHF GDYKTGFRFG QLGYDLVERR
GLKRLEARTF VCFALFVVPW MKHVGACRDL QRRAFDAANR VGDLQYATYT RNDLNSNLIF
SGESLCDALA EAEHGLAFAE KSRFGLAIDI IATQVALMRT LRGLTPKFGC LDDAQFDEAR
IERRFSENPD LAIAACWYWI RKLQARCIAG DHAAAMDAAA KAKGLLWTTA SFFEEAEYYF
YGALSHAACA DATSGDARQA HLTALAGHHG QLTVWAEHCP ENFENRAALV GAEIARIEGR
ELDAMRLYEL AIRSARANGF VHVEALANEL AARFYAAREF AVIAETYLRH AHYSYLRWRA
DGKARQLEQM HPHLRTEAFA PGPTGTITTP VEHLDLSTVI KVSQMVSGVI VLEKLIEMVM
RTAIEQAGAE RGVLILPDAG EQRITAEATI DGEMVAVHLH DQPMTDAVLP ESVLNYVLRT
RESVILDDAV ADPTFAADPY IAQHRARSIL CLPLMNQARL TGALYLENHL TTHVFTPARI
AILRLVASQA AIALENAHLY RELVEREAKI RRLVDADIIG IVVWTVEGDV LEANDAFLRM
VGYARDDLIA GSVRWTDLTP PEWREGDERV LQEIREMGSA PPFEKEFVRK DGSRVPVLIG
AATFETGRRE GVAFVLDLSE RKQAEESIRE GERRYREAQT ELAHANRVAT IGHLGASIAH
EIKQPVAATV TNAHAAVRWL RAEPPNIDEV SEILGRIIKD GNRAVDIIGR IRELVKKAPP
RKEPLDINQA IREVVELTRA EARKHDTLVQ THLADPLPLV QGDRVQLQQV LLNLLINAME
AMSGASDGAR DLLISTEKAE GNCVRVAVSD SGPGFAPDDP ERIFAPFYTT KSAGLGMGLS
ICRSIIDAHE GRMWASANVP HGAVFQFTVP TEPGTSL
//
