ID   A0A1I1E654_9BACT        Unreviewed;       773 AA.
AC   A0A1I1E654;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE            EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN   ORFNames=SAMN05421780_101657 {ECO:0000313|EMBL:SFB82705.1};
OS   Flexibacter flexilis DSM 6793.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Flexibacteraceae;
OC   Flexibacter.
OX   NCBI_TaxID=927664 {ECO:0000313|EMBL:SFB82705.1, ECO:0000313|Proteomes:UP000199514};
RN   [1] {ECO:0000313|EMBL:SFB82705.1, ECO:0000313|Proteomes:UP000199514}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 6793 {ECO:0000313|EMBL:SFB82705.1,
RC   ECO:0000313|Proteomes:UP000199514};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC         with release of beta-D-glucose.; EC=3.2.1.21;
CC         Evidence={ECO:0000256|ARBA:ARBA00000448};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC       {ECO:0000256|ARBA:ARBA00005336, ECO:0000256|RuleBase:RU361161}.
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DR   EMBL; FOLE01000001; SFB82705.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I1E654; -.
DR   STRING; 927664.SAMN05421780_101657; -.
DR   OrthoDB; 9805821at2; -.
DR   Proteomes; UP000199514; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR   Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR026891; Fn3-like.
DR   InterPro; IPR019800; Glyco_hydro_3_AS.
DR   InterPro; IPR002772; Glyco_hydro_3_C.
DR   InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR   InterPro; IPR001764; Glyco_hydro_3_N.
DR   InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR30620:SF16; LYSOSOMAL BETA GLUCOSIDASE; 1.
DR   PANTHER; PTHR30620; PERIPLASMIC BETA-GLUCOSIDASE-RELATED; 1.
DR   Pfam; PF14310; Fn3-like; 1.
DR   Pfam; PF00933; Glyco_hydro_3; 1.
DR   Pfam; PF01915; Glyco_hydro_3_C; 1.
DR   PRINTS; PR00133; GLHYDRLASE3.
DR   SMART; SM01217; Fn3_like; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
DR   PROSITE; PS00775; GLYCOSYL_HYDROL_F3; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU361161};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361161};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199514};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..773
FT                   /note="beta-glucosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5011532002"
FT   DOMAIN          698..767
FT                   /note="Fibronectin type III-like"
FT                   /evidence="ECO:0000259|SMART:SM01217"
SQ   SEQUENCE   773 AA;  85400 MW;  1ACCC1C043DD5CCB CRC64;
     MNLQSFNIKA TAQALALGML CLSQTAFAQN AQDAQIEKLI SQMTLQEKVG QMAQITLDVI
     GKGKDRYSSF EPLALDTAEL NKAILKYHVG SVLNTANNRA RTPQVWHELI NQMQAVATKK
     ARLKIPIIYG IDAIHGTTYT AGATFFPQQI GQAATFNRNL VREGAEIAAY ETRASGIRWN
     FSPVLDLGAD PRFSRQWEGY GEDPYLGTAL GLEAVKGYQG QLGQNGEIDA KHVAACLKHF
     LAYSAPASGK DRTPAYMSEQ MLREYHLPAF KAAIEAGAAT IMINSGLINN IPTHANYQIL
     TKLLKEELNF KGLVVSDWGD IENLYRRDHI AANDKEAIML AVNAGIDMSM IAYQYEVFCD
     NLVALVKEGK VKQERIDDAV RRVLRTKQQL GLFKNAVEKQ KDYPKFADKT FQQAAYNTAA
     ESITLLKNQN GVLPLAKNKK VFVTGPNANS MRTLNGGWSY SWQGEKVEDF AGQYNTILEA
     IQNEVGKANV QYAAGVSYKM TGSYYEEFAD KLEEAVAQAA QSDVIVVCVG ENSYTEKPGD
     LNDLYLSDLQ TTLVQRLAAT GKPVVVVLNE GRPRVISRFE QSVPAIVQAY LPGNFGGDAI
     ADILFGDVNP SGKLPYNYPR YPNSVSTYYH KPSEEQKKAE GMYNYEADYN PQYEFGTGLS
     YTTFKYSNLQ LSKNKLKVGE SLSVSVDVTN TGTREGKETV LLYLSDKVAS ITPDVKRLKG
     FDKISLKPNE TRKLTFTLSP AEMAFIGLDL KPTVEAGDFE VQVADQKAVF VCE
//