ID A0A1I1EG94_9RHOB Unreviewed; 900 AA.
AC A0A1I1EG94;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00022419, ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPC {ECO:0000256|HAMAP-Rule:MF_00595};
DE Short=PEPCase {ECO:0000256|HAMAP-Rule:MF_00595};
DE EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305, ECO:0000256|HAMAP-Rule:MF_00595};
GN Name=ppc {ECO:0000256|HAMAP-Rule:MF_00595};
GN ORFNames=SAMN04488094_101801 {ECO:0000313|EMBL:SFB86184.1};
OS Tropicimonas isoalkanivorans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Tropicimonas.
OX NCBI_TaxID=441112 {ECO:0000313|EMBL:SFB86184.1, ECO:0000313|Proteomes:UP000198728};
RN [1] {ECO:0000313|EMBL:SFB86184.1, ECO:0000313|Proteomes:UP000198728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19548 {ECO:0000313|EMBL:SFB86184.1,
RC ECO:0000313|Proteomes:UP000198728};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC for the tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003670,
CC ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC Evidence={ECO:0000256|ARBA:ARBA00001071, ECO:0000256|HAMAP-
CC Rule:MF_00595};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946,
CC ECO:0000256|HAMAP-Rule:MF_00595};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|HAMAP-Rule:MF_00595}.
CC -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC {ECO:0000256|ARBA:ARBA00008346, ECO:0000256|HAMAP-Rule:MF_00595}.
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DR EMBL; FOLG01000001; SFB86184.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1EG94; -.
DR STRING; 441112.SAMN04488094_101801; -.
DR Proteomes; UP000198728; Unassembled WGS sequence.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR HAMAP; MF_00595; PEPcase_type1; 1.
DR InterPro; IPR021135; PEP_COase.
DR InterPro; IPR022805; PEP_COase_bac/pln-type.
DR InterPro; IPR018129; PEP_COase_Lys_AS.
DR InterPro; IPR033129; PEPCASE_His_AS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR30523:SF6; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR Pfam; PF00311; PEPcase; 1.
DR PRINTS; PR00150; PEPCARBXLASE.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR PROSITE; PS00781; PEPCASE_1; 1.
DR PROSITE; PS00393; PEPCASE_2; 1.
PE 3: Inferred from homology;
KW Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300, ECO:0000256|HAMAP-
KW Rule:MF_00595};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_00595};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842, ECO:0000256|HAMAP-Rule:MF_00595};
KW Pyruvate {ECO:0000313|EMBL:SFB86184.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000198728}.
FT ACT_SITE 144
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT ECO:0000256|PROSITE-ProRule:PRU10111"
FT ACT_SITE 572
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00595,
FT ECO:0000256|PROSITE-ProRule:PRU10112"
SQ SEQUENCE 900 AA; 100413 MW; C4A36BD3AD97C8C7 CRC64;
MVDESVKIEG GDPQVHVDEG IRYLGKILGR VVHTQEGGDA FDTVENIRLS SIHYHRTGDE
NAYQKLQRTI SGMSEDRTLQ VLRAFTYFLH LLNISQDQET LAAGRNEPSQ LESVVEAIRE
AGFTEEQISK FFREALVSPI LTAHPTEIRR QSTMRSEFKI FRLLDDRTRA RTVGLDHSDI
DTAIEREIST LWQTHLLRRA KLTVNDEIKN GLAYFDHTFF RAVPEIQEAV HDALHLRPGE
DVPPFLRIGT WIGGDRDGNP FVTDEVLRNT FRLQAGHALS HYLSEIDQLG LELSMSTRVV
PVSDEVLALA ERSPDRSVHR QDEPYRRGLI GVFSRLAATL KEIDPEAPPP RVPLPASPYT
GPEEVLTDLD VIDTSLRANQ AGLIADGRLL SLRRKIRSFG FHLASVDLRQ NSAVHATTVA
ELFEAIAPGT GYMDLSEEAR VELLRAELNS PRSLLRPFWD YSDATEKELR IFRTAKDIID
RFGPKAICTA IISNAQSVSD VLELSVLLKQ VGLLALDGSC TISVVPLFET IADLQMGPTI
ISELLDLPEY RRVLDSQGGI QEIMLGYSDS NKDGGFVTSG WELHKAEREL VKLFRDRSLR
LRLFHGRGGS VGRGGGPARE AITAQPPGAV DGQIRLTEQG EVISSRYGHA ESGYAHLETL
VSATAEASLL PGPDLATEDA EAIMESLSEH AFRAYRSLVF ETDGFEDFFW SSTIINEIAS
LNIGSRPASR STTREITSLR AIPWVFSWAQ CRLMLPGWYG FGTAVKSWQD ANPDRGDALA
DLYRDWPFFH SMVAKVVSVI EKSDLSIASH YADLVEDTAL RDRIFSRISE EWHATADALE
AITGERPVKV EQHRTPYLDP LNHIQVSLME KVRTEETTER IKRGLLLSIN GVASGLRNTG
//
