ID A0A1I1F003_9ACTN Unreviewed; 322 AA.
AC A0A1I1F003;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:SFB92591.1};
GN ORFNames=SAMN05421773_101550 {ECO:0000313|EMBL:SFB92591.1};
OS Streptomyces aidingensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=910347 {ECO:0000313|EMBL:SFB92591.1, ECO:0000313|Proteomes:UP000199207};
RN [1] {ECO:0000313|EMBL:SFB92591.1, ECO:0000313|Proteomes:UP000199207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.5739 {ECO:0000313|EMBL:SFB92591.1,
RC ECO:0000313|Proteomes:UP000199207};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
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DR EMBL; FOLM01000001; SFB92591.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1F003; -.
DR STRING; 910347.SAMN05421773_101550; -.
DR OrthoDB; 9784013at2; -.
DR Proteomes; UP000199207; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:SFB92591.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000199207}.
FT DOMAIN 26..297
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 322 AA; 33532 MW; 4D018FFC6D0FDBCB CRC64;
MTPRESGGPP DGLPVRVAMD GLPARVRIYE VGPRDGLQNE AAAVPVRVKA EFIRRLAGAG
LTTVEATSFV HPRWVPQLAD AEQLYPELAP LAASGVRLPV LVPNERGLDR ALALGAREFA
VFASATESFA RANLNRTVAQ SLAMFAPVIR TAAEAGATRV RGYVSMCFGD PWEGPVATAD
VVRVGVRLLE LGCTELSLGD TIGVATPGQV AALLDAFGRA GVAPGRLAVH FHDTYGQALA
NTLTALRHGV TTVDASAGGL GGCPFARSAT GNLATEDLLW MLHGLGIETG VELSALAATS
RWMAGQLGRP SPSRTVRALT GD
//
