ID A0A1I1F4R0_9SPHI Unreviewed; 639 AA.
AC A0A1I1F4R0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=SAMN05421747_102117 {ECO:0000313|EMBL:SFB92140.1};
OS Parapedobacter composti.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Parapedobacter.
OX NCBI_TaxID=623281 {ECO:0000313|EMBL:SFB92140.1, ECO:0000313|Proteomes:UP000199577};
RN [1] {ECO:0000313|EMBL:SFB92140.1, ECO:0000313|Proteomes:UP000199577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22900 {ECO:0000313|EMBL:SFB92140.1,
RC ECO:0000313|Proteomes:UP000199577};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOLL01000002; SFB92140.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1F4R0; -.
DR STRING; 623281.SAMN05421747_102117; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000199577; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000199577}.
FT DOMAIN 11..66
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 68..458
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 520..598
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 639 AA; 71791 MW; D62B1DF2045F8553 CRC64;
MDLQIKSFEE YQRIYQYSVE KPEEFWAEIA EHFYWRRKWN KVLEWNFKEP NIKWFEGARL
NITENCLDRH VYKLGDKPAI IWEPNDPNEA HRVLTYKQLL DKVEQFSNVL KNNGIRKGDR
VCIYLPMVPE LVIAVLACAR IGAIHSVVFG GFSAQSIADR INDADCRLVI TADGGFRGTK
QIALKSIVDD ALVQCKSVER VIVLTRTRTP VSMIKGRDVW WEDEIKKVET QGNPPCPAEE
MNAEDLLFIL YTSGSTGKPK GVVHTCAGYM VYTGYTFTNA FQYQPDEVYF CTADIGWITG
HSYIIYGPLS QGATSLMFEG VPNWPDAGRL WDIVEKHKVN ILYTAPTAIR SLMAAGDQYV
EGKDLSTITK LGTVGEPINE EAWHWYDQKI GKGKAPIVDT WWQTETGGFL ISPIAGVTPT
VPGYAMLPLP GVQPILVDEN GQEIEGNGVS GNLCIKYPWP GMIRTTYGDH ERCRQTYFSV
YENLYFTGDG CLRDENGYYR ITGRVDDVLN VSGHRIGTAE VENAINMHSD VIESAVVGYP
HPVKGQGIYA FVIASQHHTD EDLTRQDINQ TVSRIIGAIA KPDKIQFVSG LPKTRSGKIM
RRILRKIAEG DTSNLGDTTT LLDPAVVDEI KEGAEKLRG
//
