ID   A0A1I1G039_9LACT        Unreviewed;       538 AA.
AC   A0A1I1G039;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=PTS system, maltose and glucose-specific IIC component {ECO:0000313|EMBL:SFC02550.1};
GN   ORFNames=SAMN04488102_102237 {ECO:0000313|EMBL:SFC02550.1};
OS   Alkalibacterium subtropicum.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC   Alkalibacterium.
OX   NCBI_TaxID=753702 {ECO:0000313|EMBL:SFC02550.1, ECO:0000313|Proteomes:UP000199612};
RN   [1] {ECO:0000313|EMBL:SFC02550.1, ECO:0000313|Proteomes:UP000199612}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23664 {ECO:0000313|EMBL:SFC02550.1,
RC   ECO:0000313|Proteomes:UP000199612};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FOLT01000002; SFC02550.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I1G039; -.
DR   STRING; 753702.SAMN04488102_102237; -.
DR   OrthoDB; 9764327at2; -.
DR   Proteomes; UP000199612; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1360.60; Glucose permease domain IIB; 1.
DR   InterPro; IPR036878; Glu_permease_IIB.
DR   InterPro; IPR018113; PTrfase_EIIB_Cys.
DR   InterPro; IPR003352; PTS_EIIC.
DR   InterPro; IPR013013; PTS_EIIC_1.
DR   InterPro; IPR001996; PTS_IIB_1.
DR   PANTHER; PTHR30009; CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT; 1.
DR   PANTHER; PTHR30009:SF24; PTS SYSTEM, IIBC COMPONENT; 1.
DR   Pfam; PF00367; PTS_EIIB; 1.
DR   Pfam; PF02378; PTS_EIIC; 1.
DR   SUPFAM; SSF55604; Glucose permease domain IIB; 1.
DR   PROSITE; PS51098; PTS_EIIB_TYPE_1; 1.
DR   PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW   Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        58..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        89..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        189..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        215..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        326..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        348..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        378..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        402..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          2..436
FT                   /note="PTS EIIC type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS51103"
FT   DOMAIN          456..538
FT                   /note="PTS EIIB type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS51098"
FT   ACT_SITE        478
FT                   /note="Phosphocysteine intermediate; for EIIB activity"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00421"
SQ   SEQUENCE   538 AA;  59221 MW;  28799E9CEC15C1B9 CRC64;
     MSNFKKNFQS FGKSLLFPIS LLSFMAIFLG LAAALQNPAI IEVAPFLGNE TLQLVFGFIR
     RLSALPFGYL PLLFAMSIPL GMVKRDKEVA VYAGAVGYIA MLLGMTYVLQ AQGFTAETTS
     IAYLMDMEGL SQVDATLQNS LFTNTLGIFV YNTNVIGGIL AGLMGVFLHN KFRETELHPA
     LTFYSGKRFV PIAAAIILAL VGIVLAFVWP LINQAIIAVG GLISESGSFG VFLYGFTEKI
     INPTGLHHIL NQTFRFTALG GVENIDGESL VGALQIYLYQ LDNNLAFSTD ATAFLAQGKI
     LHMVFGMPAA VLAMYKMARP EKRDRVLKFF LAGVTAVILT GITEPIEFTF IFISPILWVV
     NAIFAGLAFL VPALLNVAIG NIQGGIIDWI VFGMLQGMET GWYIYLIAGP IFFAMYYFSY
     TFIISKFNVM TIGRRESDFE DEEEVDESVS VKESDRKTAE DIINGLGGLK NITDVDNCIS
     RLRVEVADGQ LVDESLLKRT QPNGIVRPDA NTVHVVYGGR ISKMRNIVDN YMYEHKNS
//