ID   A0A1I1GCX2_9ACTN        Unreviewed;       459 AA.
AC   A0A1I1GCX2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Predicted Zn-dependent peptidase {ECO:0000313|EMBL:SFC07708.1};
GN   ORFNames=SAMN04487968_103291 {ECO:0000313|EMBL:SFC07708.1};
OS   Nocardioides terrae.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Nocardioides.
OX   NCBI_TaxID=574651 {ECO:0000313|EMBL:SFC07708.1, ECO:0000313|Proteomes:UP000198832};
RN   [1] {ECO:0000313|EMBL:SFC07708.1, ECO:0000313|Proteomes:UP000198832}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 1.7056 {ECO:0000313|EMBL:SFC07708.1,
RC   ECO:0000313|Proteomes:UP000198832};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
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DR   EMBL; FOLB01000003; SFC07708.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I1GCX2; -.
DR   STRING; 574651.SAMN04487968_103291; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000198832; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851:SF149; GH01077P; 1.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000198832}.
FT   DOMAIN          60..208
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          215..393
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   459 AA;  48924 MW;  13AA34E67969F499 CRC64;
     MTSRKTEDAT GRQTTAGRSF PVRSAEYTPS GAAQRVGTTL TLEEGPGSVV RRTVLPGGLR
     VVTEQMAGVR SAAVGVWVGV GSRDETARLH GASHFLEHLL FKGTPERTAL EISLALDAVG
     GEFNAFTTKE YTCFHARVLD EDLPLAVDVL GDMITSSLLA PDDVEAERDV ILDEIAMHDD
     DPDDVVHNLF AAQAFGEDTP LGRGIAGTTG SIEALTRDQV RRFYKKHYRP ANMVVSAAGN
     LDHADVVRQV RKAFGRRGFL SGNESPVPPR GGRAVRVSSG SVSVSRPFEQ ANLVLGLPGL
     ARDDDRRFAL SVLTTALGGG TSSRLFQEVR ERRGLAYSVY AFTGSYAETG LVGVAAGCLP
     TKLDELLKVV RSELAVLARD GIRDDELAVG KGQLRGGLVL GLEDPASRMS RLGKAELTHV
     DLLSIDEVLA RIDGVTLDEC RAVAAEIFAG PEILAVVGP
//