ID A0A1I1HZA5_9RHOB Unreviewed; 322 AA.
AC A0A1I1HZA5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Phosphoglycerate dehydrogenase {ECO:0000313|EMBL:SFC29539.1};
GN ORFNames=SAMN04488094_103346 {ECO:0000313|EMBL:SFC29539.1};
OS Tropicimonas isoalkanivorans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Tropicimonas.
OX NCBI_TaxID=441112 {ECO:0000313|EMBL:SFC29539.1, ECO:0000313|Proteomes:UP000198728};
RN [1] {ECO:0000313|EMBL:SFC29539.1, ECO:0000313|Proteomes:UP000198728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19548 {ECO:0000313|EMBL:SFC29539.1,
RC ECO:0000313|Proteomes:UP000198728};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; FOLG01000003; SFC29539.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1HZA5; -.
DR STRING; 441112.SAMN04488094_103346; -.
DR OrthoDB; 7374922at2; -.
DR Proteomes; UP000198728; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05300; 2-Hacid_dh_1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000198728}.
FT DOMAIN 30..314
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 108..284
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 322 AA; 33891 MW; 9D4449F00E90479F CRC64;
MKLVVRSQLP LGNRIARALE DLPFVSEVVV PADAEALYAA LPGATGLITM NSLYDAALAD
ALERTPSLRW LQLLSAGFEN LAAHGVPFGV TVTNAGNGRT ANVAEHALAL ALALYRGIPV
AVASQQACRW APPIAESMGT LEGARATVLG YGSIGQAIAR RLAAFDAHVV ALNRSPRQDG
IVGETRPLED LDAVLAETEI LFVAVALVPE TKHLVDARRL ALMPRGARLV NIARGEVLDT
DGLVDALGSG LLFGAGIDTT DPEPLPPDHP LWRAPGALVT PHLGGTETER SSERIVALAI
ENARRLNAKR PLKARIASLA AQ
//
