ID A0A1I1IAG2_9ACTN Unreviewed; 685 AA.
AC A0A1I1IAG2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=SAMN04487968_105214 {ECO:0000313|EMBL:SFC33329.1};
OS Nocardioides terrae.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=574651 {ECO:0000313|EMBL:SFC33329.1, ECO:0000313|Proteomes:UP000198832};
RN [1] {ECO:0000313|EMBL:SFC33329.1, ECO:0000313|Proteomes:UP000198832}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.7056 {ECO:0000313|EMBL:SFC33329.1,
RC ECO:0000313|Proteomes:UP000198832};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; FOLB01000005; SFC33329.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1IAG2; -.
DR STRING; 574651.SAMN04487968_105214; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000198832; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:SFC33329.1};
KW Cilium {ECO:0000313|EMBL:SFC33329.1};
KW Flagellum {ECO:0000313|EMBL:SFC33329.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000198832};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 94..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 189..211
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 231..249
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 270..288
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 685 AA; 72105 MW; AD01B67F23877207 CRC64;
MKSLTKLGVP IGIVMIVVML VVPLPAVLLD LLIALNITAG LLILLTAMFV PRPLDFAAFP
SVLLVMTLFR LALNVSATRL VLLHGFAGKV IDTFGHFVVG GSLIVGLIVF AILLVIQFVV
ITNGAGRVAE VGARFTLDAM PGKQMAIDAD LNSGLIDEDE ARRRRAEVHA EADFYGAMDG
ASKFVKGDAI AAIIITIVNL IGGFAIGVAQ GGMSFSEAIN TYSLLSVGDG LVSQIPALLL
SVATGLIVTR SVSNGDMGSD ILAQILRRKL PLRIAGFAGL ALCLIPGLPK LPFIVAGGLM
LLASSRVDES EPAEQLAPAA ELEPSPDSPE MLAQDILVDP LGLELAADII DLVDASTGGD
LLDRVKALRR KVAGDLGVVI PPVRTRDNLE LPMNTYAITL FGVEVARGQA PRGTVLAISD
DLAALPGTPT REPVFGLDAK WIPAEMRHQA EISGATVVDR ASVITTHLAE IVNTQAGRLL
GREDVRLLTD IVKRSHPVVI EELTPALLTL GEIQRVLRGL LDEQVSVRDL VRIFEALSLR
GAVTKDTDQL VEAARTALGQ AVVAPYLTDG VVSAISFDPR LEQSMLEALR STDQGAVLAL
DPELAQNMLV QLHNLATAGE DTGVRPVLVC APQLRAAIRR LVAPALDRLP VLSYSEIAGV
HSVQSLGSVS AVRADAPGAV LAVSA
//
