ID A0A1I1L5G4_9RHOB Unreviewed; 816 AA.
AC A0A1I1L5G4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Small-conductance mechanosensitive channel {ECO:0000313|EMBL:SFC68287.1};
GN ORFNames=SAMN05421762_1785 {ECO:0000313|EMBL:SFC68287.1};
OS Pseudooceanicola nitratireducens.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Pseudooceanicola.
OX NCBI_TaxID=517719 {ECO:0000313|EMBL:SFC68287.1, ECO:0000313|Proteomes:UP000231644};
RN [1] {ECO:0000313|EMBL:SFC68287.1, ECO:0000313|Proteomes:UP000231644}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 29619 {ECO:0000313|EMBL:SFC68287.1,
RC ECO:0000313|Proteomes:UP000231644};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; FOLX01000001; SFC68287.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1L5G4; -.
DR STRING; 517719.SAMN05421762_1785; -.
DR OrthoDB; 9799209at2; -.
DR Proteomes; UP000231644; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR022249; DUF3772.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF12607; DUF3772; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000231644};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 199..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 509..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 547..570
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 576..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 124..180
FT /note="DUF3772"
FT /evidence="ECO:0000259|Pfam:PF12607"
FT DOMAIN 592..659
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 668..749
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
FT REGION 763..816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 816 AA; 88938 MW; DF1E6BD25601CDD2 CRC64;
MIERLRQAAL WVVLMTTLLI GSVVSVFAQD IDYDAWVDVA ARAETAIGAE AASEQAFEVL
REELTNWRQT FQAARSQNAA AIEAVRAQID ALGPKPEEGE EAPETAQQRD TLNTRLNDLR
APVQRAEVAY SRADALIAQI DRILRDRQAD RLLELGPTPL NPVLWPQAVT ALVDFFTRTA
DDIQNNWTNP ARRADFQQVL PMTVFFLTLA FILTLRGRYW VERLASRLQD RDRTAERWLA
GFVVSIGQII VPVVGFICLA IAGLSTEMLG ARGEMLVQAL PAAGFQFFAA RWLGGRLFPR
TDKFELPLAL DGIRRAEGRI HALTLGLVLF LIEPLRRIQD FAGWGAEVTS VLTFPLLVVA
ALALLRLAQL LLRHAKETAE TEVDVKSRLL TILSRITMAV AVAGPIFAAI GYFNAGEALV
YPTIASLMLM ALLVVLQRLV DELYILFTRN RDGVKEALTP VLAGFALVLV SIPAFALIWG
ARVTDLTELW TRFLAGFSLG DTRISPTDFL TFVVIFAIGY VATRMVQSAL RTTVLPKTKL
DVGGQNAVAS GMGYVGIFAA GVIAVTSAGL DLSSLAIVAG ALSVGIGFGL QNIVSNFVSG
IILLIERPVA IGDWIQVGGQ MGYVRDISVR STRIETFDRT DVIVPNADLV SGTVTNWTRG
NLVGRIIVPV GVAYGSNTRQ VEKILQEVAE AQPMVLLNPP PFILFKGFGA DSMDFEIRAI
LRDVTAILQV QTEMNHQITE RFAEAGIEIP FAQRDIWLRN PEALRPDTAP PAATPVAEPL
TRDEAQAAEQ QLTPEDLPGS QDGETGDASG DGGEGR
//
