ID A0A1I1LS82_9BURK Unreviewed; 543 AA.
AC A0A1I1LS82;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Choline dehydrogenase {ECO:0000313|EMBL:SFC73808.1};
GN ORFNames=SAMN05216344_13715 {ECO:0000313|EMBL:SFC73808.1};
OS Polaromonas sp. OV174.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Polaromonas.
OX NCBI_TaxID=1855300 {ECO:0000313|EMBL:SFC73808.1, ECO:0000313|Proteomes:UP000218980};
RN [1] {ECO:0000313|EMBL:SFC73808.1, ECO:0000313|Proteomes:UP000218980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OV174 {ECO:0000313|EMBL:SFC73808.1,
RC ECO:0000313|Proteomes:UP000218980};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; FOKZ01000037; SFC73808.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1LS82; -.
DR STRING; 1855300.SAMN05216344_13715; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000218980; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000218980}.
FT DOMAIN 5..296
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 391..529
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
FT BINDING 84
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 543 AA; 58793 MW; 94CF26AA68CD82C3 CRC64;
MQETYDYVIV GAGSAGCTLA NRLSEDPGVM VLLLEAGGWD RDPWIKIPLG WGQILQNRLH
DWMYYAEPEA NVDGRRVECA RGKVVGGSSS TNAMAYVRGN PGDFDRWASR YGLPGWTYKH
VLPYFKRQEN WEQGAGGERA ADGPVNVQRC KYQDPLIGAY ANAAKAAGYG WTEDYNTSSQ
EGFSHLQMTI RNGARCSTAV AYLRPALKRP NLTVKVKILA SRVTLESGKA TGVEYLENGQ
KKVAQASREV LLCSGVINTP QLLMLSGIGD PVQLAAHGIK VKVPLKGVGA NLQDHVSVVV
MYERKSPGPF HRMMRMDRIA PAIAQAYLAG TGFASDIPGG VVGFAKSDPE QEVPDLQVLL
TAAPLPAWPY LSPFKKPFKD GFAVRTVLLH PQSRGRIELT SKDPAAAPRI FQNFLGCEAD
WKATRAAIRM VRKIARQSPL APFIGREVAP GPQAESDEAI DAFIRKTAIT VHHPAGTCRM
GTVDDPMSVV DAELRVIGVQ GLRVVDASVM PDLTSGNINA PVIMIAEKAA DLITGRPLLA
PAA
//
