ID   A0A1I1PUY7_9BURK        Unreviewed;       356 AA.
AC   A0A1I1PUY7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=DNA polymerase III subunit delta {ECO:0000256|ARBA:ARBA00017703};
DE            EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN   ORFNames=SAMN05216321_11263 {ECO:0000313|EMBL:SFD13482.1};
OS   Cupriavidus sp. OV038.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=1855313 {ECO:0000313|EMBL:SFD13482.1, ECO:0000313|Proteomes:UP000199583};
RN   [1] {ECO:0000313|EMBL:SFD13482.1, ECO:0000313|Proteomes:UP000199583}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OV038 {ECO:0000313|EMBL:SFD13482.1,
RC   ECO:0000313|Proteomes:UP000199583};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC         Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC         ChEBI:CHEBI:173112; EC=2.7.7.7;
CC         Evidence={ECO:0000256|ARBA:ARBA00024632};
CC   -!- SIMILARITY: Belongs to the DNA polymerase HolA subunit family.
CC       {ECO:0000256|ARBA:ARBA00034754}.
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DR   EMBL; FOKX01000012; SFD13482.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I1PUY7; -.
DR   Proteomes; UP000199583; Unassembled WGS sequence.
DR   GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   CDD; cd18138; HLD_clamp_pol_III_delta; 1.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 1.20.272.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR   InterPro; IPR032780; DNA_pol3_delt_C.
DR   InterPro; IPR010372; DNA_pol3_delta_N.
DR   InterPro; IPR005790; DNA_polIII_delta.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   NCBIfam; TIGR01128; holA; 1.
DR   PANTHER; PTHR34388; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR   PANTHER; PTHR34388:SF1; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR   Pfam; PF14840; DNA_pol3_delt_C; 1.
DR   Pfam; PF06144; DNA_pol3_delta; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE   3: Inferred from homology;
FT   DOMAIN          24..197
FT                   /note="DNA polymerase III delta N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06144"
FT   DOMAIN          223..321
FT                   /note="DNA polymerase III subunit delta C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14840"
SQ   SEQUENCE   356 AA;  38704 MW;  0173B0C6190BE0F5 CRC64;
     MQLKLDGLDA HLKQAQAKGM APLYVVHGDE HLLVLEAVDR LRRTAREAGF SERDVLVAER
     GFHWSQLVEA QQSMSLFGDR KIVELRIPTG KPGKDGGEAL RAVAAQPSPD VVMLVTLPRL
     DFATSKSAWF QALESAGVSI KVDAVDRTRL PAWVGERLGL QQQRVEPGEA GRRALQFIAD
     KVEGNLLAAH QEIQKLGLLY PPGVLTFDQV HDAVLNVARY DVFKLSEAML GGDVPRLTRM
     LEGLRGEGEA TVLVLWALTE EIRVLSKVRQ GLAAGKPAGV LMRELRVWGP RERLVPQAAQ
     RLALPQLEAA LAMAARLDRQ VKGLSDLPGA GGLGGSLPAE PWDGLLQLAL MIARPA
//