ID A0A1I1QJ84_9RHOB Unreviewed; 836 AA.
AC A0A1I1QJ84;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Cu+-exporting ATPase {ECO:0000313|EMBL:SFD22095.1};
GN ORFNames=SAMN04488094_12127 {ECO:0000313|EMBL:SFD22095.1};
OS Tropicimonas isoalkanivorans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Tropicimonas.
OX NCBI_TaxID=441112 {ECO:0000313|EMBL:SFD22095.1, ECO:0000313|Proteomes:UP000198728};
RN [1] {ECO:0000313|EMBL:SFD22095.1, ECO:0000313|Proteomes:UP000198728}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19548 {ECO:0000313|EMBL:SFD22095.1,
RC ECO:0000313|Proteomes:UP000198728};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362081}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IB subfamily. {ECO:0000256|ARBA:ARBA00006024,
CC ECO:0000256|RuleBase:RU362081}.
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DR EMBL; FOLG01000021; SFD22095.1; -; Genomic_DNA.
DR RefSeq; WP_054540621.1; NZ_FOLG01000021.1.
DR AlphaFoldDB; A0A1I1QJ84; -.
DR STRING; 441112.SAMN04488094_12127; -.
DR OrthoDB; 9807843at2; -.
DR Proteomes; UP000198728; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0015662; F:P-type ion transporter activity; IEA:UniProt.
DR CDD; cd00371; HMA; 2.
DR CDD; cd02094; P-type_ATPase_Cu-like; 1.
DR Gene3D; 3.30.70.100; -; 2.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR017969; Heavy-metal-associated_CS.
DR InterPro; IPR006122; HMA_Cu_ion-bd.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01511; ATPase-IB1_Cu; 1.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 1.
DR NCBIfam; TIGR00003; copper ion binding protein; 1.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF8; COPPER-TRANSPORTING ATPASE 2; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 2.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00943; CUATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 2.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS01047; HMA_1; 2.
DR PROSITE; PS50846; HMA_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362081};
KW Cell membrane {ECO:0000256|RuleBase:RU362081};
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Copper transport {ECO:0000256|ARBA:ARBA00022796};
KW Ion transport {ECO:0000256|ARBA:ARBA00022796};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU362081};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW Reference proteome {ECO:0000313|Proteomes:UP000198728};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362081};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362081}; Transport {ECO:0000256|ARBA:ARBA00022796}.
FT TRANSMEM 163..186
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 198..215
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 236..258
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 264..283
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 417..439
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 445..468
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 761..780
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 786..808
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT DOMAIN 5..70
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT DOMAIN 72..138
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
SQ SEQUENCE 836 AA; 87051 MW; 9DD6E31B6728A229 CRC64;
MPEPKQISLP IEGMSCASCV GRVDRALNAI DGVEDVSVNL ASETARMSVD ALKRIPDIIE
SLRELGYPAR KARAELTIAA MSCASCVGRV DKALAAVPGV VEVNVNLASE TATVVYVEGL
VTTSDLIESS GAAGYPATVA TAQAGDDRVA RKEEEAQALA KRVTFAAILA LPVFLIEMGG
HVIPAVHMLI ETTIGQQTSW LLQFVLTTIV LFGPGRTFYT KGFPALFRGA PDMNSLVAVG
TGAAYLYSVV ATFVPSVLPD TLRTVYFEAA AVIVVLILLG RFLEARAKGR TGAAIQKLLG
LQARTARVMR DGESVEIEID ALVQGDIVIV RPGERIAVDG EVIEGTSRVD ESMLTGEPIP
AEKGAGDTVT GGTVNGAGSL QFLATRVGAD TTLAQIIRMV EEAQGAKLPI QGLVDRITLW
FVPAVMAIAA ATVLVWLFFG PDPALTMALV AGVSVLIIAC PCAMGLATPT SIMVGTGRAA
EMGVLFRKGD ALQQLDSVDV VALDKTGTVT EGRPALTDLV LAEGFDRTTT LSKMAAVESL
SEHPVADAIV RAARAEGAPL VAAEGFQSVT GYGVRAVVED VEVLVGADRY MAREGIDVSA
LSPEETKIAS KGRTALYAAI DGRVAAVIGV ADPVKPASRA AIAALHEKGL AVAMITGDKR
ETAEAIARET GIDHVIAGVL PDGKVAALDS LRQGNKRIAF VGDGINDAPA LAHADVGIAI
GTGTDVAIES ADVVLMSGDL RGVVNAFEVS RRTMRNIRQN LFWAFAYNVA LIPVAAGVLY
PAFGLLLSPI LAAGAMALSS VFVLTNALRL RRIAPAMDEQ RAIPAEMAAA TPAPAE
//
