ID   A0A1I1QQK4_9CLOT        Unreviewed;       346 AA.
AC   A0A1I1QQK4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE            EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN   ORFNames=SAMN05421842_12650 {ECO:0000313|EMBL:SFD24329.1};
OS   Clostridium uliginosum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=119641 {ECO:0000313|EMBL:SFD24329.1, ECO:0000313|Proteomes:UP000199263};
RN   [1] {ECO:0000313|EMBL:SFD24329.1, ECO:0000313|Proteomes:UP000199263}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12992 {ECO:0000313|EMBL:SFD24329.1,
RC   ECO:0000313|Proteomes:UP000199263};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC         Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC         ChEBI:CHEBI:140347; EC=3.5.2.6;
CC         Evidence={ECO:0000256|ARBA:ARBA00001526};
CC   -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC       {ECO:0000256|ARBA:ARBA00009009}.
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DR   EMBL; FOMG01000026; SFD24329.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I1QQK4; -.
DR   STRING; 119641.SAMN05421842_12650; -.
DR   OrthoDB; 9775096at2; -.
DR   Proteomes; UP000199263; Unassembled WGS sequence.
DR   GO; GO:0008800; F:beta-lactamase activity; IEA:InterPro.
DR   GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR045155; Beta-lactam_cat.
DR   InterPro; IPR000871; Beta-lactam_class-A.
DR   PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR   PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13354; Beta-lactamase2; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   3: Inferred from homology;
KW   Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199263}.
FT   DOMAIN          122..318
FT                   /note="Beta-lactamase class A catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF13354"
SQ   SEQUENCE   346 AA;  40061 MW;  7BE73BA89C5213C7 CRC64;
     MRITKKHFLI ILILFFCLLT LLIYTFRSNS ELKSIKSDNT TKLYNNVYEN SRDDAASTII
     NTQALKKYLI PKKLNTGISL DKDLLNLDLT NEFKLSILHN NKYNLEDRIS LYLGTDKENV
     GLIYYDLNSD EYINFNEDDI FVAASTYKVS LNVLTYERAK ENKNLLNTTI KYEDKYYEEG
     TGVLQNLTDI PNMKIQDLLD LSIINSDNIA TNMVGSYFGG HAQARKEVWN MFDVPISYSD
     NVTTPNAEFK ILKHIYDNKD DINYAHLIKV LQSTDCHSRI DKYLPYDIVA HKVGSSNEYI
     HDIGLVLDKN PYILIIYTKD LDNPEEKIAQ ISKAIYEYQI TEKEQT
//