ID A0A1I1SRZ1_9LACO Unreviewed; 215 AA.
AC A0A1I1SRZ1;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Deoxyadenosine kinase {ECO:0000313|EMBL:SFD49214.1};
DE SubName: Full=Deoxynucleoside kinase {ECO:0000313|EMBL:RHW50366.1};
GN ORFNames=DS834_06875 {ECO:0000313|EMBL:RHW50366.1}, DS835_06795
GN {ECO:0000313|EMBL:RHW53804.1}, SAMN04487792_1091
GN {ECO:0000313|EMBL:SFD49214.1};
OS Lactobacillus bombicola.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1505723 {ECO:0000313|EMBL:SFD49214.1, ECO:0000313|Proteomes:UP000199599};
RN [1] {ECO:0000313|Proteomes:UP000199599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R-53102 {ECO:0000313|Proteomes:UP000199599};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SFD49214.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R-53102 {ECO:0000313|EMBL:SFD49214.1};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000265862, ECO:0000313|Proteomes:UP000283380}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BI-4G {ECO:0000313|EMBL:RHW50366.1,
RC ECO:0000313|Proteomes:UP000283380}, and OCC3
RC {ECO:0000313|EMBL:RHW53804.1, ECO:0000313|Proteomes:UP000265862};
RA Motta E.V.S., Moran N.A.;
RT "Genome sequences of six Lactobacillus spp. isolated from bumble bee
RT guts.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DCK/DGK family.
CC {ECO:0000256|ARBA:ARBA00007420}.
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DR EMBL; QOCU01000007; RHW50366.1; -; Genomic_DNA.
DR EMBL; QOCV01000010; RHW53804.1; -; Genomic_DNA.
DR EMBL; FOMN01000005; SFD49214.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1SRZ1; -.
DR STRING; 1505723.SAMN04487792_1091; -.
DR Proteomes; UP000199599; Unassembled WGS sequence.
DR Proteomes; UP000265862; Unassembled WGS sequence.
DR Proteomes; UP000283380; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019136; F:deoxynucleoside kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01673; dNK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002624; DCK/DGK.
DR InterPro; IPR031314; DNK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR PANTHER; PTHR10513:SF15; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL; 1.
DR Pfam; PF01712; dNK; 1.
DR PIRSF; PIRSF000705; DNK; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Kinase {ECO:0000313|EMBL:SFD49214.1};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Transferase {ECO:0000313|EMBL:SFD49214.1}.
FT DOMAIN 5..209
FT /note="Deoxynucleoside kinase"
FT /evidence="ECO:0000259|Pfam:PF01712"
FT ACT_SITE 79
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-1"
FT BINDING 9..17
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT BINDING 141..145
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
SQ SEQUENCE 215 AA; 24875 MW; 83962FA6BF72F3E6 CRC64;
MIQVIVLSGP IGAGKSSLTS ILAEHLGTQA FYEGVDNNPV LPLYYQDMKR YTFLLNIYLL
NHRLAQINQA IQEKNSVSDR SIYEDALFFR MNAENNVADP TEFKIYDSLL ENMLEDTPGN
PSKKPDLLIY IHVSLDTMLK RIEKRGRSFE QLSTDPSLKD YYARLINYYE PWYENYDASP
KMAIDGDQYD FIIDEHAKKE VLHQIDNKLH EVGNL
//
