ID A0A1I1U2F7_9ACTN Unreviewed; 384 AA.
AC A0A1I1U2F7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Protein-L-isoaspartate O-methyltransferase {ECO:0000256|ARBA:ARBA00013346};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
DE AltName: Full=L-isoaspartyl protein carboxyl methyltransferase {ECO:0000256|ARBA:ARBA00031350};
DE AltName: Full=Protein L-isoaspartyl methyltransferase {ECO:0000256|ARBA:ARBA00030757};
DE AltName: Full=Protein-beta-aspartate methyltransferase {ECO:0000256|ARBA:ARBA00031323};
GN ORFNames=SAMN05421773_12257 {ECO:0000313|EMBL:SFD65051.1};
OS Streptomyces aidingensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=910347 {ECO:0000313|EMBL:SFD65051.1, ECO:0000313|Proteomes:UP000199207};
RN [1] {ECO:0000313|EMBL:SFD65051.1, ECO:0000313|Proteomes:UP000199207}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.5739 {ECO:0000313|EMBL:SFD65051.1,
RC ECO:0000313|Proteomes:UP000199207};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FOLM01000022; SFD65051.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1U2F7; -.
DR STRING; 910347.SAMN05421773_12257; -.
DR Proteomes; UP000199207; Unassembled WGS sequence.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR027573; Methyltran_FxLD.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR04364; methyltran_FxLD; 1.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:SFD65051.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000199207};
KW Transferase {ECO:0000313|EMBL:SFD65051.1}.
SQ SEQUENCE 384 AA; 40876 MW; 2B1D3547E4340A67 CRC64;
MVGELEGMGV LQSKAVAKAV ATVPRHLFAA DQPLESAYAA NKALVIKRDG SGNALSSLSA
THIQAVMLEQ AEIEPGMRVL EVGSGGYNAA LLAELVGEAG TVVTADIDAE IVERARACLD
AAGYGRVQVV LADADGGVPE HAPFDRIIVT AGAWDIPPAW LEQMSERGRI VVPLRMRGLT
RSFAFDREDG GLVSASYRLC GFVPMQGSGA YTERLVPIAD GIALQVDDQR QEFDTEALAA
AVHTPRLEVW SGAAFDLPDE LELFLATSTP QMAMLHGSKQ LVDQGALALS VTRGVPALVV
GGSFAYRTKR PNEETGGFES GVFAHGPEAE AVAARYVDLL RRWASDHRRR GAARIRYVRM
PEGTAEPSAG VVAKRFGAVQ ISWS
//
