ID A0A1I1W0V7_9BACT Unreviewed; 1054 AA.
AC A0A1I1W0V7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Two-component system, chemotaxis family, CheB/CheR fusion protein {ECO:0000313|EMBL:SFD88639.1};
GN ORFNames=SAMN05518672_103700 {ECO:0000313|EMBL:SFD88639.1};
OS Chitinophaga sp. CF118.
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Chitinophaga.
OX NCBI_TaxID=1884367 {ECO:0000313|EMBL:SFD88639.1, ECO:0000313|Proteomes:UP000199596};
RN [1] {ECO:0000313|EMBL:SFD88639.1, ECO:0000313|Proteomes:UP000199596}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF118 {ECO:0000313|EMBL:SFD88639.1,
RC ECO:0000313|Proteomes:UP000199596};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FOMK01000003; SFD88639.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1W0V7; -.
DR STRING; 1884367.SAMN05518672_103700; -.
DR OrthoDB; 9816309at2; -.
DR Proteomes; UP000199596; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0008984; F:protein-glutamate methylesterase activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-UniRule.
DR CDD; cd16434; CheB-CheR_fusion; 1.
DR CDD; cd00075; HATPase; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.180; Methylesterase CheB, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR035909; CheB_C.
DR InterPro; IPR022642; CheR_C.
DR InterPro; IPR000780; CheR_MeTrfase.
DR InterPro; IPR022641; CheR_N.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR000673; Sig_transdc_resp-reg_Me-estase.
DR PANTHER; PTHR24422; CHEMOTAXIS PROTEIN METHYLTRANSFERASE; 1.
DR PANTHER; PTHR24422:SF25; CHEMOTAXIS PROTEIN METHYLTRANSFERASE; 1.
DR Pfam; PF01339; CheB_methylest; 1.
DR Pfam; PF01739; CheR; 1.
DR Pfam; PF03705; CheR_N; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF13596; PAS_10; 1.
DR PRINTS; PR00996; CHERMTFRASE.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00138; MeTrc; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47757; Chemotaxis receptor methyltransferase CheR, N-terminal domain; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52738; Methylesterase CheB, C-terminal domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50122; CHEB; 1.
DR PROSITE; PS50123; CHER; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Chemotaxis {ECO:0000256|PROSITE-ProRule:PRU00050};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00050}.
FT DOMAIN 1..187
FT /note="CheB-type methylesterase"
FT /evidence="ECO:0000259|PROSITE:PS50122"
FT DOMAIN 206..442
FT /note="CheR-type methyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50123"
FT DOMAIN 844..1054
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 653..712
FT /evidence="ECO:0000256|SAM:Coils"
FT ACT_SITE 13
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00050"
FT ACT_SITE 39
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00050"
FT ACT_SITE 129
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00050"
SQ SEQUENCE 1054 AA; 119176 MW; EC77CE194A08A5CB CRC64;
MKEGQYIIAI GASAGGMAQI NTFFDFTPLD SVSYIVIQHL SADYKSMMAA LLAKHSKLNV
LEAESGMTVE MNKVYMIPSK SSMTIKDGKL LLADKQKGVN LTIDTFFESL AEEMGEKAIG
IVLSGTGQDG TAGITAIKKA GGLVIVSKPE ASEYDQMPIS AIATGLVNYT AYPEEMPLLI
QRYVGGKVKE AEINIDEDDE KVITGITELI KDKLPEDFSG YKKSTILRRI RRRASLLNFN
TIENYLGLLK KDMAELQTLV KDFLISVTAF FRDKAAFQVL EESFIPEMIE SKHDEDIKVW
VAGCATGEEA YTFAILMRER LDAANKKNTV KIFATDIDDD ALQFAAKGYY SESIEKDVSP
ERLEHFFSKD NKGYRVKPSI REMLIFAHHD LVKNPPYCNI DFISCRNLLI YMNPTLQKKI
LNMLHFGMRY GGYLFLGPSE NVTDFMPHLE ERNKKWKIYK NIEAKRMQSF ENFTSPAFIE
GKGYVAPQRS AKIAEGKSTV TEIKIDTELL VEMGYTGLLI DENDQVLDVF GESTRFLSQK
MFVHHLPDLL SKSLQIAFIT AGIEADKTNK LVAIKGIKVT GIDSPVTLSV KPLAANEKGI
KTRLVLFFED GVESNTQNTF TFDESFFRDK YTVNVEQELA LTKEKLASTH ELLNASNENM
QSFNEELLSA NEEMQSTNEE MQSVNEELHT INAEYQSKIR ELSDLNDDLN NYFRSNVNGQ
IFVNKDLRLM KFSPGAETHI NLLEIDIGRP LSNISTNIRF ETIEKDIRKV LDDGCVITRE
LHAVNGKWFQ VMTMPYLRKG NNETDGAIIT FNDISELKKI QQELSHSNQI LKAINTDLDN
FVFTSSHDLL SPMNNIEQII YFIKEREKVL DKETRDYVNM LSVAVGRFRS VIKEMAAIGK
MESEMFNMEI IDIDEIIGEV LASIEWRISS DHANIQTQLE VKNINFSRKN CRSMIYNLIN
NALKFKSPSR YPEITITTKD LPDYVLLSVK DNGIGISKHK IETIFKMYRQ LNAGTDGQGL
GLFLINKIID ASGGKVEVES QPDVGTEFRI FIKK
//
