ID   A0A1I1W3U7_9BACT        Unreviewed;       399 AA.
AC   A0A1I1W3U7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=Exodeoxyribonuclease VII large subunit {ECO:0000313|EMBL:SFD89835.1};
GN   ORFNames=SAMN05216167_108125 {ECO:0000313|EMBL:SFD89835.1};
OS   Spirosoma endophyticum.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae; Spirosoma.
OX   NCBI_TaxID=662367 {ECO:0000313|EMBL:SFD89835.1, ECO:0000313|Proteomes:UP000198598};
RN   [1] {ECO:0000313|EMBL:SFD89835.1, ECO:0000313|Proteomes:UP000198598}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 26130 {ECO:0000313|EMBL:SFD89835.1,
RC   ECO:0000313|Proteomes:UP000198598};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FOLQ01000008; SFD89835.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I1W3U7; -.
DR   STRING; 662367.SAMN05216167_108125; -.
DR   OrthoDB; 9802795at2; -.
DR   Proteomes; UP000198598; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR   GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR   InterPro; IPR003753; Exonuc_VII_L.
DR   InterPro; IPR020579; Exonuc_VII_lsu_C.
DR   InterPro; IPR025824; OB-fold_nuc-bd_dom.
DR   PANTHER; PTHR30008; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR   PANTHER; PTHR30008:SF0; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR   Pfam; PF02601; Exonuc_VII_L; 2.
DR   Pfam; PF13742; tRNA_anti_2; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198598}.
FT   DOMAIN          6..112
FT                   /note="OB-fold nucleic acid binding"
FT                   /evidence="ECO:0000259|Pfam:PF13742"
FT   DOMAIN          149..331
FT                   /note="Exonuclease VII large subunit C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02601"
FT   DOMAIN          313..395
FT                   /note="Exonuclease VII large subunit C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02601"
SQ   SEQUENCE   399 AA;  45031 MW;  2CC97E53A21EEE9A CRC64;
     MSPIRLSDLA FTLEAVIDEA FGQKAVWVVA ETSDIKNYPD RGYCFLTLVD RESAGRETLA
     KMEACIWRRN YHTIGNFEQE TGVAFARNIQ LLLLVSVSYS PVYGLRLEIL KIDPSYTLGN
     LERERQAVLD SLVKDHPDLI WLEAGQYITA NQLLPRPAVM QRLALITAPN SDGWRDFRHE
     LAQNPFGYDF VVDEFLTQVQ GQGAERAICG QLERIRTNGV AYDAVVIVRG GGSQLDFGSF
     DTYLMGQTVA GFGIPILAGI GHERNISITD LLCHQSVKTP TKAAAFLIEH NRQFEESCLQ
     LRERLRMVAR EALLSARENL DRETERLRFV SHTYLRGRHT DLAEKAVTLR HLDPSNVLKR
     GYALLLRNGR ILTHTTNIQP NETLQVQMYD GSINVVVSQ
//