ID A0A1I1XS10_9ACTN Unreviewed; 333 AA.
AC A0A1I1XS10;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=3-oxoacyl-[acyl-carrier-protein] synthase-3 {ECO:0000313|EMBL:SFE09418.1};
GN ORFNames=SAMN05216251_101484 {ECO:0000313|EMBL:SFE09418.1};
OS Actinacidiphila alni.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Actinacidiphila.
OX NCBI_TaxID=380248 {ECO:0000313|EMBL:SFE09418.1, ECO:0000313|Proteomes:UP000199323};
RN [1] {ECO:0000313|EMBL:SFE09418.1, ECO:0000313|Proteomes:UP000199323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3510 {ECO:0000313|EMBL:SFE09418.1,
RC ECO:0000313|Proteomes:UP000199323};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. FabH family.
CC {ECO:0000256|ARBA:ARBA00008642}.
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DR EMBL; FONG01000001; SFE09418.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1XS10; -.
DR STRING; 380248.SAMN05216251_101484; -.
DR OrthoDB; 9815506at2; -.
DR Proteomes; UP000199323; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00830; KAS_III; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR013747; ACP_syn_III_C.
DR InterPro; IPR013751; ACP_syn_III_N.
DR InterPro; IPR004655; FabH.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR00747; fabH; 1.
DR PANTHER; PTHR34069; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 3; 1.
DR PANTHER; PTHR34069:SF2; BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III; 1.
DR Pfam; PF08545; ACP_syn_III; 1.
DR Pfam; PF08541; ACP_syn_III_C; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000199323};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 117..193
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08545"
FT DOMAIN 242..330
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08541"
SQ SEQUENCE 333 AA; 34663 MW; DD3738EFF1AEDDC9 CRC64;
MKAEIAVPDG ARHTRILGVG AYRPRSVVDN HEVCRYIDSS DEWIRSRTGI VTRRWAGPDE
TLGVMAEHAA SKAIAAAGLT PDRITCVIAA TFTHLMQTPA IATEIAHRIG ATEAAAFDIT
AGCAGFVHGV VLASDAVRAR GGHVLVVGVE RMTDLLDLSD RSTAFIFGDG AGAVVIGPSD
TPGIGPAVWG ADGSQADAIE QTAPWDVLKD DPTHKFPALR QDGQRVFRWA VYEMAKVAKE
ALDVAGIGPA DLDTFIPHQA NERIIDSMAK SIGLPPDVTV AKDIVTNGNT SGASIPQAME
AVLASGAAHS GDTALLLGYG SGLSYAAVVA TLP
//
