ID A0A1I1YWR6_9ACTN Unreviewed; 1042 AA.
AC A0A1I1YWR6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Serine phosphatase RsbU, regulator of sigma subunit {ECO:0000313|EMBL:SFE23919.1};
GN ORFNames=SAMN05216251_102219 {ECO:0000313|EMBL:SFE23919.1};
OS Actinacidiphila alni.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Actinacidiphila.
OX NCBI_TaxID=380248 {ECO:0000313|EMBL:SFE23919.1, ECO:0000313|Proteomes:UP000199323};
RN [1] {ECO:0000313|EMBL:SFE23919.1, ECO:0000313|Proteomes:UP000199323}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.3510 {ECO:0000313|EMBL:SFE23919.1,
RC ECO:0000313|Proteomes:UP000199323};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FONG01000002; SFE23919.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1YWR6; -.
DR STRING; 380248.SAMN05216251_102219; -.
DR Proteomes; UP000199323; Unassembled WGS sequence.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16936; HATPase_RsbW-like; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR Pfam; PF13581; HATPase_c_2; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000199323}.
FT DOMAIN 141..170
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 1..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1042 AA; 109593 MW; 12CB33AAA27EE43A CRC64;
MDEITRQPAT SDADHPADRS ARYEQREQQD LHDHPEHPEH LDHGPADQAA PPADRTRRDT
ERHPRRRSHA AGHPQGGTAD GAGAPSAEDA KDESVNEAEA DVGAEVRTEA GRDTDTAAAP
AVPRPAPAGD AGVSALLRLA VLCVDPDGRI SYWNRGAEEL FGHRWEHVFG HRASGLLTPA
RAAAGAVRTS AAPHQDTLDL LDDLTHPAWA GALAATDRDG TLKDVLWWTY RIAEPGGHSL
LAIAAHAKPL RTGSLRIALG GRLLPYTAEG PQRQDISVAA VLGPTVDQAQ ALSLAARLSS
VLPGVSAGRL DRLLRQIAPL GPPALEVDGG TRLPVTPHDY ALLAAAARAD RTDRSLRREL
LPGPRPGAAP KPSAPGGASV PNGAGPVPAE AADNSPGTGT GTADDRSSAS ALTAVPFPSL
TSLSADPGTL DPQEPLVGQP PLPGLAPVLG GHPHLAPSGT PHAPGAPGSP NAPTGNGTYP
LGRPYAPHLP GNALDEQLAL LRETGSVVGS TLDLQTTARE LCAVTVPRFA DFAAVLIVDQ
LFSDSEPPKD DAPAATVLVR RVAIAHEGAP GPWETALPEG ELLSLAVDGI VPRLGDHVLV
PVVDPAVAPD IALDLGVPAL GPLLPGHSMI VAPLTARGTV LGRVCFLRGP GRRPFDARDA
ATATEIVARG AVHIDNARLH RLESRAAATL QRSMMPARPP RIPGVRIAHH YMPGDRQAQV
GGDWFDAIQL PGGRVALIVG DVMGHGLQAA AVMGQFRTAV ITMAALDLPP AQVLRHLDNL
AHRLGTEHLA TCVYAVYDPI HRSLTLANAG HIPPVLAGYD GRSELLEIPG GAPIGVGGVP
FETVEIPVPD GSWLVLCTDG LVEVRGEGID AGLAALCATV IEPEQTPEDV CGQILGRLHS
EDRRDDVALL VARFEGIVPE DVVKWTLRLD QSEVARARDL TRRQLAAWGL ERLSDTTELL
VSELVTNAIR AASYEVELRL MRVGKLLVEV SDDNHNLPQL QRADADDEQG RGLALVSHLS
RRWGTSRKAV GKVVWFELPL PA
//
