ID A0A1I1Z4F6_9FIRM Unreviewed; 368 AA.
AC A0A1I1Z4F6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Electron transfer flavoprotein alpha subunit {ECO:0000313|EMBL:SFE26432.1};
GN ORFNames=SAMN02910327_00802 {ECO:0000313|EMBL:SFE26432.1};
OS Peptostreptococcaceae bacterium pGA-8.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae.
OX NCBI_TaxID=1520829 {ECO:0000313|EMBL:SFE26432.1, ECO:0000313|Proteomes:UP000242361};
RN [1] {ECO:0000313|Proteomes:UP000242361}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=pGA-8 {ECO:0000313|Proteomes:UP000242361};
RA Varghese N., Submissions S.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR000089-1};
CC Note=Binds 1 FAD per dimer. {ECO:0000256|PIRSR:PIRSR000089-1};
CC -!- SIMILARITY: Belongs to the ETF alpha-subunit/FixB family.
CC {ECO:0000256|ARBA:ARBA00005817}.
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DR EMBL; FONK01000005; SFE26432.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I1Z4F6; -.
DR STRING; 1520829.SAMN02910327_00802; -.
DR OrthoDB; 9770286at2; -.
DR Proteomes; UP000242361; Unassembled WGS sequence.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd01715; ETF_alpha; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR014730; ETF_a/b_N.
DR InterPro; IPR001308; ETF_a/FixB.
DR InterPro; IPR033947; ETF_alpha_N.
DR InterPro; IPR014731; ETF_asu_C.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR43153; ELECTRON TRANSFER FLAVOPROTEIN ALPHA; 1.
DR PANTHER; PTHR43153:SF1; ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF01012; ETF; 1.
DR Pfam; PF00766; ETF_alpha; 1.
DR PIRSF; PIRSF000089; Electra_flavoP_a; 1.
DR SMART; SM00893; ETF; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000089-1};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000089-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000242361}.
FT DOMAIN 12..225
FT /note="Electron transfer flavoprotein alpha/beta-subunit N-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00893"
FT BINDING 249
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 274..275
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 288..292
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 305..312
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 326
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
SQ SEQUENCE 368 AA; 40076 MW; CF404EC12C1B2DAB CRC64;
MANINFDEYK NIWVFVEQRN GKLMNVALEL LGEGHKLSRD ISDETKVCAL LIGDGIENLA
QECFEYGADC VYLIEDEKLK QYTTDGYTKV IADAVNEFKP DIFLYGATHI GRDLAPRVAA
RLKTGLTADC THLDVSVAEY IKFAEENTTL NTKSLNPEDP NKNLKMTRPA FGGNLMATIV
CPNHRPQMAT VRPGVMQKME PVAGATGEII RIKPEISDAD IHIQVVEVVK SAKELVSLTD
ADIICSAGRG IGDASGFDLM KKFADKVGGV VGSSRACVDA GWIDHSHQVG QTGTTVKPKI
YFACGISGAI QHLAGMQNSD IIVAINKDPD SPIFEVADYG IVGDLYKVIP EIMAEWDNAE
ALYDATTK
//
