ID   A0A1I2ACW3_9BACI        Unreviewed;       343 AA.
AC   A0A1I2ACW3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   SubName: Full=Pyruvate dehydrogenase E1 component beta subunit {ECO:0000313|EMBL:SFE41801.1};
GN   ORFNames=SAMN05192532_101794 {ECO:0000313|EMBL:SFE41801.1};
OS   Alteribacillus iranensis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Alteribacillus.
OX   NCBI_TaxID=930128 {ECO:0000313|EMBL:SFE41801.1, ECO:0000313|Proteomes:UP000199516};
RN   [1] {ECO:0000313|EMBL:SFE41801.1, ECO:0000313|Proteomes:UP000199516}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23995 {ECO:0000313|EMBL:SFE41801.1,
RC   ECO:0000313|Proteomes:UP000199516};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR   EMBL; FONT01000001; SFE41801.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2ACW3; -.
DR   STRING; 930128.SAMN05192532_101794; -.
DR   Proteomes; UP000199516; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Pyruvate {ECO:0000313|EMBL:SFE41801.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199516}.
FT   DOMAIN          22..197
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   343 AA;  37878 MW;  DF73F87933C263F8 CRC64;
     MSLISANKKN KTNDFALGQK NITMVQAITD ALDVMLERDE RVMLLGEDIG KNGGVFRATD
     GLQKKYGEDR VVDTPLSEAG IIGTGVGLAV NGMRPVLEIQ FLGFIYPAFE QIATHVTRMR
     MRTRGELTVP MVIRAPYGAG VRAPEIHSDS TEAYFTHMPG IKVICPSSPY DAKGLLISAM
     EDPDPVLFME SMRLYRSGKE EVPEGYYKEE IGKGKKVKEG KDVTVITWGA MVKTAKEAAD
     SMENRDIECD VIDVRTLYPL DQDIIADSVQ KTGRVVIVHE AHETGGVGND ILSVINKQAF
     MYLKAPIEKV TGFDVPVPMF SLEDHYLPSA ARIQTAIHKV YSF
//