ID   A0A1I2AYE4_9ACTN        Unreviewed;       350 AA.
AC   A0A1I2AYE4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN   ORFNames=SAMN05216251_103281 {ECO:0000313|EMBL:SFE48974.1};
OS   Actinacidiphila alni.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Actinacidiphila.
OX   NCBI_TaxID=380248 {ECO:0000313|EMBL:SFE48974.1, ECO:0000313|Proteomes:UP000199323};
RN   [1] {ECO:0000313|EMBL:SFE48974.1, ECO:0000313|Proteomes:UP000199323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.3510 {ECO:0000313|EMBL:SFE48974.1,
RC   ECO:0000313|Proteomes:UP000199323};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FONG01000003; SFE48974.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2AYE4; -.
DR   STRING; 380248.SAMN05216251_103281; -.
DR   OrthoDB; 9805663at2; -.
DR   Proteomes; UP000199323; Unassembled WGS sequence.
DR   GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   CDD; cd05288; PGDH; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR041694; ADH_N_2.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR045010; MDR_fam.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR   PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR   Pfam; PF16884; ADH_N_2; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199323}.
FT   DOMAIN          34..348
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   350 AA;  35716 MW;  2B7C938309E9774B CRC64;
     MSAPLSAAPA PQTPPRSARE VRVARAPRGL PVPGDFTVER APLPAPGPGQ LLVRNSHFLV
     FPGLRTLLGG ETDGVPLPPL RAGDTLFGPA VGEVVAAPDG AGARPGDTVR HLLGWRDWAL
     VPADQCEVLD GTLPDPVAYL AQGSSAYGAL TRLAPVRPGD TVLVTGAAGA VGSLAGQIAR
     LLGAGRVLGS TGSPWKAERL TAELGYDAVV PRGQGRFADR LAEAAPDGID VLLDTVGGEQ
     LAAAVGAARQ GARFALVGAL SGQLAADRAG GSAPAAIDSY RLVVKGVSVR GYAGGDHPEV
     EAEWTERFGA WLRAGEIRFP HTTVGGIGRA PHVLPELIAG RHFGAAIVEP
//