ID   A0A1I2BD18_9ACTN        Unreviewed;       316 AA.
AC   A0A1I2BD18;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Ca-activated chloride channel family protein {ECO:0000313|EMBL:SFE53193.1};
GN   ORFNames=SAMN05421541_102211 {ECO:0000313|EMBL:SFE53193.1};
OS   Actinoplanes philippinensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=35752 {ECO:0000313|EMBL:SFE53193.1, ECO:0000313|Proteomes:UP000199645};
RN   [1] {ECO:0000313|EMBL:SFE53193.1, ECO:0000313|Proteomes:UP000199645}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 43019 {ECO:0000313|EMBL:SFE53193.1,
RC   ECO:0000313|Proteomes:UP000199645};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FONV01000002; SFE53193.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2BD18; -.
DR   STRING; 35752.SAMN05421541_102211; -.
DR   OrthoDB; 8882959at2; -.
DR   Proteomes; UP000199645; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR22550; SPORE GERMINATION PROTEIN; 1.
DR   PANTHER; PTHR22550:SF19; UPF0353 PROTEIN RV1481; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199645};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        292..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          88..276
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   316 AA;  33909 MW;  982CABF7BEBC0FFB CRC64;
     MIRFLEPWWL LTLLPVLAMA GAYVWRQFRK RQYAMRFTNV DLLRTLAPKG LGWRKHVSAA
     AFLLMLGALA AATARPSVDT EEPLERATVM LAIDVSLSMQ AEDVEPSRIE AAQEAAKAFV
     NELPPSYNLG LVSFAKAANV LVAPTKDRSS VLSAIDALTL AEATATGEAV FTSLDAIRTV
     PSDGADGAPP ARIVLLSDGY RTSGRSIEDA ATAAAQANVP VSTIAFGTDT GVVDIRGSVQ
     RVPVDRLSLQ DLAEQTKGYF YEAASVSELK QVYEDMGSSI GHRTEPREVT QWYAAIGLLL
     GLAGAATSLL WTSRLP
//