ID A0A1I2BNI5_9ACTN Unreviewed; 649 AA.
AC A0A1I2BNI5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Succinate dehydrogenase subunit A {ECO:0000313|EMBL:SFE57714.1};
GN ORFNames=SAMN05421541_102435 {ECO:0000313|EMBL:SFE57714.1};
OS Actinoplanes philippinensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=35752 {ECO:0000313|EMBL:SFE57714.1, ECO:0000313|Proteomes:UP000199645};
RN [1] {ECO:0000313|EMBL:SFE57714.1, ECO:0000313|Proteomes:UP000199645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43019 {ECO:0000313|EMBL:SFE57714.1,
RC ECO:0000313|Proteomes:UP000199645};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FONV01000002; SFE57714.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2BNI5; -.
DR STRING; 35752.SAMN05421541_102435; -.
DR OrthoDB; 9805351at2; -.
DR Proteomes; UP000199645; Unassembled WGS sequence.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000199645}.
FT DOMAIN 47..453
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 514..648
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 342
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 649 AA; 71634 MW; 9C3016CFABAB49C7 CRC64;
MSANDFWAEG EPVFDKAAPD GPVETRWERR KFSAKLVNPA NRRKLTVIVV GTGLAGGSAA
ATLAEAGYRV KSYCYQDSPR RAHSIAAQGG INAAKNYRND GDSVYRLFYD TVKGGDFRAR
ESNVYRLAQV SVNIIDQCVA QGVPFAREYG GLLDNRSFGG TQVSRTFYAR GQTGQQLLLG
AYQALERQIG LGNVEMNARH EMLELIIVDG KARGIVVRDM VTGEITTEFA DAVVLASGGY
GNVFFLSTNA KGCNVTASWR AHRKGALFAN PCYTQIHPTC IPESGSHQSK LTLMSESLRN
DGRVWVPKNA ADCQKPAGEI AEEDRDYYLE RIYPSFGNLV PRDIASRAAK NVCDEGRGVG
PGGLGVYLDF ADAIKRLGRK AVEAKYGNLF EMYERITGED PYETPMRIYP AVHYTMGGLW
VDYDLQSTIP GLFVVGEANF SDHGANRLGA SALMQGLADG YFVLPNTISN YLAAGPFPAV
QATDAPVVEA RKEVEDRIAK FLSIDGDRTV DSFHRELGQI MWEYCGMERT EEGLTKAIGL
IRALKEEFWT RVKVPGKGEE LNQNLEKAGR VADFIELGEL MCIDALHRRE SCGGHFRAES
QTPDGEALRH DDEFSYAAAW EYFGADGKPV LHKEDLNFEY VHPSTRSYK
//
