ID   A0A1I2CFV0_9BACT        Unreviewed;       812 AA.
AC   A0A1I2CFV0;
DT   12-APR-2017, integrated into UniProtKB/TrEMBL.
DT   12-APR-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN   ORFNames=SAMN05444380_11611 {ECO:0000313|EMBL:SFE67237.1};
OS   Thermophagus xiamenensis.
OC   Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinilabiliaceae;
OC   Thermophagus.
OX   NCBI_TaxID=385682 {ECO:0000313|EMBL:SFE67237.1, ECO:0000313|Proteomes:UP000181976};
RN   [1] {ECO:0000313|EMBL:SFE67237.1, ECO:0000313|Proteomes:UP000181976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19012 {ECO:0000313|EMBL:SFE67237.1,
RC   ECO:0000313|Proteomes:UP000181976};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FONA01000016; SFE67237.1; -; Genomic_DNA.
DR   RefSeq; WP_010527629.1; NZ_FONA01000016.1.
DR   AlphaFoldDB; A0A1I2CFV0; -.
DR   STRING; 385682.SAMN05444380_11611; -.
DR   eggNOG; COG1033; Bacteria.
DR   InParanoid; A0A1I2CFV0; -.
DR   OrthoDB; 9805018at2; -.
DR   Proteomes; UP000181976; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000181976};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        220..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        270..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        315..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        341..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        607..626
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        633..655
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        709..728
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        734..760
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          242..369
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   812 AA;  91550 MW;  F982DCE8D2186916 CRC64;
     MWIRTASFIL RNRFPILIVL TILTVFLGVQ SREIEMSYQY APLLPEDDPA SLDYQDFIKE
     FGNEGNLIVL GIQDSTFFEV QHFSAWEQLT QNLKKINGIT SVFSVSDAFT LKKNLQKKKF
     ELSPVFREIN NQSVLDSLYQ TFDALPFYKY LIYNPETHSY LMAITLDREV LESEARVPLI
     NEIKKCANAY ALSTGNKVHI SGLPYIRVET AEMIKKELNM FIWLALAITA VIIFLFFRSF
     KVVIFSMLVV GMAVIWALGI QALAGFKITI LTGMIPPLII VIGIPNSVFF LNKFHYEFRK
     HGNKIKSLQR VIQKIGNATF LTNLTTASGF ATFVFTSSKL LIEFGIMAAI NIMVVFILSL
     TLIPIIFSFL SDPREKHVRH LNNRFFEVII NKLVHISLNH KKVVYSGALG LIIFGGYGIS
     QMKTTGYMLD DIPHDHTLYK DLDFFEKHFS GLMPLEIMID TQKPKGVMQP QNLRKIDALQ
     QKLTEFPEIS KGLSIAEVVK FARQAFYNGN PGFYSLPGSM EHKFIMSYVP QSNTTIPGVV
     NSFVDSTGQK TRISFRMADV GTNKMEVLNN KIGAIVDSVF TPSKYVTSLT GSSVVFFKGT
     EYLVRNLFIS LGLAILLIAS FMSWMFRSKR MVLVSLIPNL VPLITTAALM GVFNIPIKPS
     TILVFSIAFG ISVDDTIHFL SKYRQELGET NWSIRAATVL ALKETGRSMI YTSVILFFGF
     GIFTVSSFGG TVALGALVAL TLLVALFSNL ILLPSLLLGL ERLITNQSFK EPMLTIYDED
     EDIDMDELKI KKPVENIDPK EQEIKMEAHV EN
//