ID   A0A1I2CS26_9BACT        Unreviewed;       415 AA.
AC   A0A1I2CS26;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Zinc protease {ECO:0000313|EMBL:SFE70583.1};
GN   ORFNames=SAMN04488541_1005113 {ECO:0000313|EMBL:SFE70583.1};
OS   Thermoflexibacter ruber.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Thermoflexibacteraceae;
OC   Thermoflexibacter.
OX   NCBI_TaxID=1003 {ECO:0000313|EMBL:SFE70583.1, ECO:0000313|Proteomes:UP000199513};
RN   [1] {ECO:0000313|EMBL:SFE70583.1, ECO:0000313|Proteomes:UP000199513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GEY, DSM 9560 {ECO:0000313|Proteomes:UP000199513};
RA   de Groot N.N.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261}.
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DR   EMBL; FONY01000005; SFE70583.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1I2CS26; -.
DR   STRING; 1003.SAMN04488541_1005113; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000199513; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF17; PROTEIN YHJJ; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 1.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:SFE70583.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000199513};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          16..128
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          168..344
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   415 AA;  47518 MW;  147515E70B37EB63 CRC64;
     MIEYQSFILD NGLKVYVHED RSVATAAVNI LYDVGSRDEH PDKTGFAHLF EHLMFGGSKN
     IPEYDKPLQR VGGENNAFTS PDITNYYITL PSQNLETAFW LESDRMMSLS FKPEVLEVQR
     KVVIEEFKQR YLNQPYGDIW LRLRPLAYKT HPYQWATIGK DIAHIEQATM DDVKDFFYRY
     YLPNNAIMVI AGNVNLDEVK KLSEKWFAPI PAGEVPQRQL PQEQEQRESR FLEIEANVPA
     TMIYKVYQMC ERTSPDYIPT DLLSDVLGRS KSSRLHQKLV QEQKLFSAAS AFVTGSIDKG
     LFCISGKLHE GVSIENAAKA LQEVIDELVN EKISEAELQK VKNQVESTLI LGEIEVLPRA
     MNLAYHALLG NPDLINKEAE YIQAVTVEQI QQIAKKVLRP DNCSTLYYKS KNNNR
//