ID A0A1I2DJA9_9BURK Unreviewed; 658 AA.
AC A0A1I2DJA9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN04489711_105237 {ECO:0000313|EMBL:SFE80529.1};
OS Paracidovorax wautersii.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Paracidovorax.
OX NCBI_TaxID=1177982 {ECO:0000313|EMBL:SFE80529.1, ECO:0000313|Proteomes:UP000199119};
RN [1] {ECO:0000313|EMBL:SFE80529.1, ECO:0000313|Proteomes:UP000199119}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 27981 {ECO:0000313|EMBL:SFE80529.1,
RC ECO:0000313|Proteomes:UP000199119};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FONX01000005; SFE80529.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2DJA9; -.
DR STRING; 1177982.SAMN04489711_105237; -.
DR Proteomes; UP000199119; Unassembled WGS sequence.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF00072; Response_reg; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00448; REC; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}.
FT DOMAIN 21..137
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 149..193
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 293..511
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 541..658
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 69
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 590
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 658 AA; 71504 MW; E145E27CA874FE04 CRC64;
MLNAMPNSGI IAPTIDRSRH TVLVVDDNPA TRYSTARVIR AAGFLTEEAD SGGAALALAG
TGIAAVVLDV HLPDMSGFDV CRALRGDPRT TFMPIVHLSA AYVQSEHRVA GLNAGADAYM
VHPVEPPLLI ATLQALIRAR LAEDKLRSSQ NRFRAIYDQA PVAMMLIDER GVFTDVNPAA
AALLQRPAES LIGTPVAALA APVWREFVQE RTCAPTASAW HGELPLLRGD GHQLPLDWSM
SEPVEPGVRI GIAKDLTERI ELERRHEEVL EREQAARVLA ERHSRTKDDF VAVLSHELRT
PLTLITGWAH MLKRPGVTPD TLARGISAIE RGVQAQSRII SDILDVSRLA SGKLRLHREW
ADPVELALIS LDAVRETADA KKIAIVLDRH NAGTPAWLDA TRFQQIIWNL VTNSIKFSEA
GSTVRIAMQR EGDELTVVVQ DEGMGIAPEF LPHLFGRFTQ SGPPNNRTHG GLGLGLSIVK
HLVELHGGQI QAESAGPGQG STMRARLLVA PDEHSHTTDA SAASDSVLLD DGSQRRLQDK
DILVVEDNAD TSEMLGIVLS DQGARVRSVE NYDAALQELD RQWPDLLVSD IGLPGKDGYQ
LIAAIREREA AAGRPDRLRA VALTAFARPQ DRERALAAGF DAHLGKPLQP HLLLQLLV
//
