ID A0A1I2DW80_9BACT Unreviewed; 934 AA.
AC A0A1I2DW80;
DT 12-APR-2017, integrated into UniProtKB/TrEMBL.
DT 12-APR-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675};
DE EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};
GN ORFNames=SAMN05444380_12056 {ECO:0000313|EMBL:SFE84894.1};
OS Thermophagus xiamenensis.
OC Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinilabiliaceae;
OC Thermophagus.
OX NCBI_TaxID=385682 {ECO:0000313|EMBL:SFE84894.1, ECO:0000313|Proteomes:UP000181976};
RN [1] {ECO:0000313|EMBL:SFE84894.1, ECO:0000313|Proteomes:UP000181976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19012 {ECO:0000313|EMBL:SFE84894.1,
RC ECO:0000313|Proteomes:UP000181976};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|RuleBase:RU000675};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
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DR EMBL; FONA01000020; SFE84894.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2DW80; -.
DR STRING; 385682.SAMN05444380_12056; -.
DR eggNOG; COG1874; Bacteria.
DR InParanoid; A0A1I2DW80; -.
DR OrthoDB; 703126at2; -.
DR Proteomes; UP000181976; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000675};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000675};
KW Reference proteome {ECO:0000313|Proteomes:UP000181976}.
FT DOMAIN 57..400
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
SQ SEQUENCE 934 AA; 106666 MW; 28123CC1C456A9B6 CRC64;
MIRFFILVFL SGMGMSLSGQ KYYLDASKIS DQVMGGHLKM GNSGEADRKI EVNNRYLTLG
GKPIIPVMGE MHYSRIERDR WEDVILKMKA NGINIIASYV FWNHHEELEG QFDWTGNKDL
RSFLKLVQKH GLWVYPRIGP WCHGEVRNGG TPDWILDKNY LTDRSNHPVY QAYVDRWYQQ
VARQMGGLYY KDGGPIVGIQ LENEYWRGKG GEAHILWLKE TARKYGMDVP LYTITGWRNT
SLPQDEVIPL WGGYPAVPWA THIQTITENL NYIFDAPVNM ENIGNEETPS NGYQPDYSRY
PYFTCEIGVG NQLSYHRRPV IGPLDGLAIA TIKTGSGSNM LGYYVFAGGS NPSGILNTLQ
EEQYYTGYWN EYPKVSYDFQ AAIRETGELA PSYHQVKKLH YFLNAFGHRL APLSPVIPAG
NSDMEALQYA IRSDGRAGFL FGVNYYRGIP KPVQKNVQFH IRLKNEALIF PGRPVNIEDS
TIFIWPFNFK MDNVLLKYAT AQPVGKFRRA DERVWIFFQN NSIIPELAFD ESTVKEISTQ
WGKMDKRNGM LVVKDFQPGK KHWIDVRDYS DNRIKIMVLS HAEADQMWVL NSRGRSHFFL
SDANLYLDQN RLHVFDTDTC FQVLGLNSDM QPLSSGKGRV KPVSEGLFNG FRICVPGKEL
KVNYQCEDIF DRSDWLKATP NDFSGKKHLY HKIFIKEFAL MNSSSVQSAV MKLFTDVPLR
LNVNNRWVSQ RVDTSMVNFI DLCGYVQNGE NVLMLDVPYV AGDGALAARL DVEYFNGDKI
EIVTDGSWLT TTDYRIPVPG RPIRGLKAPE LTKPRSVEMD RAGRPVTYCL TIPEDYNDKL
ANTFLRIRYA GDRAEARIGH RLVADNFNNG TPWSISLRKL GSLPETEPLV ITIEPLASGG
KIYFEKPLLE GHKGVAQLLS VDLEREFNYD FELK
//
