ID A0A1I2DZ60_9RHOB Unreviewed; 700 AA.
AC A0A1I2DZ60;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=SAMN04488523_11157 {ECO:0000313|EMBL:SFE85698.1};
OS Sulfitobacter brevis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Sulfitobacter.
OX NCBI_TaxID=74348 {ECO:0000313|EMBL:SFE85698.1, ECO:0000313|Proteomes:UP000198977};
RN [1] {ECO:0000313|EMBL:SFE85698.1, ECO:0000313|Proteomes:UP000198977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11443 {ECO:0000313|EMBL:SFE85698.1,
RC ECO:0000313|Proteomes:UP000198977};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
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DR EMBL; FOMW01000011; SFE85698.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I2DZ60; -.
DR STRING; 74348.SAMN04488523_11157; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000198977; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:SFE85698.1};
KW Cilium {ECO:0000313|EMBL:SFE85698.1};
KW Flagellum {ECO:0000313|EMBL:SFE85698.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000198977};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 26..44
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 50..69
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 121..144
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 214..235
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 255..273
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 312..331
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 700 AA; 75114 MW; 3189FF69A86766DF CRC64;
MALPDTTTAA KPAFSFGKLG RDNRDIGFAI GVMLILAMLF VPLPPFLLDL GLAISLSLSV
LILMVALWIG TPLEFNSFPT LLLVVTMLRL ALNVSSTRLI LARGHEGPGA AGNVIEGFAQ
FIVGGDFVIG IVVFIILVII NFVVITKGST RIAEVAARFS LDAMPGKQMA IDADLGAGVI
NEQEAKTRRR IVEEESSFFG AMDGASKFVR GDAVAGLIIV LINVFGGILI GMLSHDLSVT
QALSNYTVLT IGDGLVTQIP ALIVSLAAGL LVTKGGTSGA ANEAVLGQLS NFPKALYMAS
ALTFGIGWLP GFPLTIFLPL AAGMAGFGYV MQKQIAERLA KDTQEAKDAA TPTDAPSDGV
ADMLRVDDVR LDLGAGLVPM ITSVDAALPG KVKSLRSLFI KDYGFVLPPV RIKDDSDLPS
LTYSISLQGV EAARGEIEPL MMMVINPTGE DIDLPGKRTR EPTFGLEAIW VDEATASEAE
LRGMTVVDPE SVVTTHLTEV IKEHMPEILT YSATQELIEG QDKDYQKLLA DSSNNSPAVM
LQHVLQALLA ERVSIRNLPK IIEAVAEASA NTKNIRTVIE HARGKLAKQI CQTLKDPQGY
VPVINLNGEW ERELVNSIST ANGEDTFLMS PSRVQEFVLA MRKEIQKHSA ADHWPAILVT
PQARPYVRSI LERVSPTTQV ISHNEVHRKA SLRTIGTVGS
//
